Senior Associate Scientist, In Vivo Pharmacology & Toxicology
- Employer
- bluebird bio
- Location
- Cambridge, MA, United States
- Start date
- Dec 6, 2018
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- Discipline
- Science/R&D, Biotechnology, Pharmacology, Toxicology
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Hotbed
- Genetown
Job Details
*This role is most appropriate for candidates with Bachelors or Masters degrees*
Responsibilities:
- Design, plan and execute in vivo studies including xenogeneic mouse tumor models and murine stem cell engraftment models in collaboration with research scientists.
- Perform routine injections (sc, ip, iv) in mice, monitor animal health, collect blood samples, measure tumors, perform necropsies and collect and record data.
- Analyze data using software including Excel and GraphPad Prism; prepare and present data to various groups within the organization.
- Establish new animal models as needed, including pilot studies for model development and troubleshooting.
- Contribute to the initial and recurrent training of junior vivarium staff members.
- Perform routine cell culture and maintain tumor cell lines used in xenograft models.
Qualifications:
- BA/BS or MS with 7-10 years' experience in the biotechnology or pharmaceutical industry
- Experience with in vivo animal studies required, including animal handling, performing routine injections, necropsy, collection of blood and tissues
- Expertise with murine intravenous injections
- Perform in vitro assays in support of PK / PD studies including ELISA, ELISPOT, flow cytometric and qPCR analysis of blood, serum and tissue samples - preferred
- Desire and drive to learn and understand the basic biologic mechanisms underpinning our immunotherapy and gene therapy products
- Experience in maintaining a laboratory notebook and following written protocols
- Familiarity with programs such as Excel, GraphPad Prism and PowerPoint for data entry, analysis and presentation
- Team player with excellent oral and written communication skills and "do-what-it-takes" attitude
- Independently motivated, detail-oriented and excellent problem-solving abilities
- Excellent organizational skills towards multi-tasking in an extremely fast-paced environment with changing priorities
- Comfortable with rapidly changing schedules and priorities
- Be ready to embrace the principles of the bluebird bio culture: b colorful, b cooperative, and b yourself
Company
bluebird bio is leading the gene therapy revolution. We have nearly 15 years of scientific and clinical experience at the forefront of gene therapy, with deep expertise in rare diseases and immuno-oncology, a proven scientific and lentiviral-based manufacturing platform, and a complementary set of tools such as gene editing.
We are a patient- and purpose-driven, product-oriented organization. Our diverse flock of bluebirds is united by a singular focus: a passionate commitment to changing the lives of patients and supporting each other on this journey. At bluebird bio, we will work like crazy with a never-give-up, little-but-mighty attitude, as exemplified by our namesake, the Eastern Bluebird.
we are always innovating, never stopping and never giving up.
Stock symbol: BLUE
Stock exchange: NASDAQ
- Website
- http://www.bluebirdbio.com/
- Phone
- 339-499-9300
- Location
-
60 Binney St
Cambridge
MA
02142
US
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