Scientist, Immunology - Immune Cell Signaling & Molecular Biology

Employer
AbbVie
Location
Worcester, MA, US
Posted
Dec 04, 2018
Ref
1808761
Required Education
Bachelors Degree
Position Type
Full time
We are seeking a highly motivated and creative scientist with background in Immunology, immune cell signaling and molecular biology to join the AbbVie Global Biologics Discovery organization in Worcester, MA. This individual will work in drug discovery cross-functional teams both internally and externally to characterize and test recombinant proteins for different therapeutic areas including Immunology, Neuroimmunology and Immuno-oncology.

Responsibilities:

  • Perform mammalian cell culture and independently develop, run, analyze and troubleshoot in vitro assays, such as ELISA, western blot, FACs & cell-based activity assays.
  • Use developed in vitro assays to validate and characterize novel therapeutic proteins
  • Demonstrate innovation and strong problem solving, analytical skills and be a team player.
  • Work collaboratively with matrixed project teams and members of the Global Biologics Group to drive innovation and deliver novel therapies for patients
  • Develop productive collaborations and communication with other groups across therapeutic areas
  • Timely documentation of experiments and activities in electronic archive systems
  • Engage colleagues in cross-disciplinary scientific discussion, present scientific data to internal and external audiences and publish research in peer-reviewed journals


Position will be hired based on level of experience.

  • BS in Immunology, molecular biology, or related field with at 5-7+ years of relevant experience or MS with 2-5+ years of experience
  • Extensive expertise in mammalian cell culture/transfection and in vitro analytical techniques for protein characterization (such as ELISA, western blot, FACs & cell-based activity assays) is required
  • Experienced in cell isolation and culture of primary immune cells (dendritic cells, macrophages and T cells) is required
  • Proficiency in a wide range of molecular biology and immunology techniques (Molecular cloning, RNA isolation, c-DNA synthesis, qPCR, proliferation/cytotoxicity assays)
  • Experience in extracellular matrix biology in mammalian systems is a plus
  • Experience with in vivo rodent models (IBD, CIA, xenograft) is a plus
  • Strong communication and organization skills, especially the ability to work across multiple scientific disciplines and functions


Equal Opportunity Employer Minorities/Women/Veterans/Disabled