Sr R&D Specialist Immuno-Oncology

Location
Tarrytown, New York, US
Posted
Dec 02, 2018
Ref
13920BR
Required Education
Bachelors Degree
Position Type
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases . Summary. The successful candidate will contribute to the discovery and validation of new immune-oncology drug targets and will be involved in screening of therapeutic human antibodies to these targets using in vitro primary immune cells assays and preclinical mouse cancer models . Responsibilities. The successful candidate will develop/optimize primary immune cell bioassays, perform experiments utilizing in vivo mouse tumor models for discovery and development of therapeutic cancer targets, and write detailed experimental protocols. The candidate is expected to work independently in a creative, collaborative, and dynamic team environment. The candidate is expected to perform experiments, analyze data, and to present his/her research findings to interdisciplinary teams. Strong technical, analytical and time-management skills, and attention to details are required for this position . Requirements. TECHNICAL SKILLS REQUIRED - Knowledge of the basics of cellular and molecular immunology - Perform in vivo experiments utilizing tumor models in mice. Expertise with animal handling, different methods of compound administration i.v , i.p , s.c , etc , and tissue /blood collection - At least intermediate-level knowledge and practical experience with flow cytometry minimum eight fluorochromes , including cell surface staining, intracellular staining, data acquisition and analysis. Familiar with flow cytometers, such as FACSCanto and Fortessa. Experience with panel design is plus -Processing, staining and flow-cytometric analysis of mouse tumors, tissues and blood as well as human blood for immune markers -Strong knowledge of FlowJo, Excel, Prizm, PowerPoint computer programs is required . PREFERRED - Ability to develop and optimize a variety of in vitro/ex vivo immune cell-based assays, including antigen-specific T cell assays, T cell proliferation and functional assays, monocytes activation assay - Experience with measurements of cytokines levels in blood is preferred by MSD . CORE COMPETENCIES - Strong organizational and time-management skills including the ability to handle and prioritize multiple tasks simultaneously - Creativity and independency in work - Ability to effectively collaborate within cross-functional teams - Clear and professional verbal and written communication - Ability to clearly present data at the internal meetings . Minimal educational requirements . Bachelors Degree, Masters Degree preferred 8+ years relevant experience . This position will require the individual to pass a physical before beginning employment . This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business . To all agencies . Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid . Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.