Bristol-Myers Squibb Company

Scientist, Single B Cell Technology (37)

Location
Redwood City, CA, US
Posted
Dec 01, 2018
Ref
R1512038
Required Education
Doctorate/PHD/MD
Position Type
Full time
Scientist - Single B cell technology

Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. Driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

We are looking for a highly motivated scientist to join the lead discovery effort within the antibody lead generation group. This is an exciting opportunity to make a significant impact within a department that is driving the biologics therapeutics pipelines in BMS. In this role the scientist is expected to develop and use the single B cell cloning and associated platforms to expedite the process and deliver high quality lead antibody molecules.

Major responsibilities:

• Contribute to develop and optimize the existing single B cell cloning capacity within the protein therapeutics department. Expand the scope of applications of single B cell protocol and harmonize it with associated supporting platforms.
• Fully integrate the single B cell cloning protocol into lead generation pipelines.
• Be a champion in the lead discovery process and collaborate with biology project leaders closely to progress respective pipelines.
• Present data at project meetings.
• Stay informed and contribute to the vision in the technology development space especially in single cell analytics and gene capture.
• Excellent written and oral skills are necessary.
• Accomplish goals under project team time lines.

Qualifications:

• Ph.D. in molecular biology or immunology with 2+ years of relevant experience.
• High proficiency in all critical molecular biology techniques with focus on high throughput, high sensitivity gene rescue from single cells or tissues of interest. Past experience with antibody V gene rescue from single B cells is required.
• Proficiency in cell biology skills such as FACS. Target-centric cell sorting or selection experience is a plus.
• Proficiency in large dataset analysis is highly desirable.
• In-depth knowledge of B/T cell biology and humoral and cell mediated immune responses.
• Highly innovative and self-motivated.
• Excellent time management and organizational skills.
• Demonstrated ability to work in a multidisciplinary biologics discovery team.