Scientist I
- Employer
- Frederick National Laboratory for Cancer Research
- Location
- Frederick, MD, USA
- Start date
- Nov 29, 2018
View more
- Discipline
- Science/R&D, Biotechnology
- Required Education
- Doctorate/PHD/MD
- Position Type
- Full time
- Hotbed
- BioCapital
Job Details
KEY ROLES/RESPONSIBILITIES
- The Scientist I will support research efforts to define the role of transcriptional regulators in myeloid cell development, and their potential role in leukemogenesis.
- This work will be accomplished performing both molecular and stem cell biology techniques, cloning and construction of lentiviral and retroviral vectors, quantitative RT-PCR, analysis of transcription factor function (EMSA and CHIP assays), and experience working with hematopoietic cells in vitro and in vivo.
- The Scientist I will breed, type and maintain transgenic, conventional and targeted KO mouse strains.
- The Scientist I will sort bone marrow stem cells by flow cytometry and oversee all bone marrow transplantation studies including tracking donor cells by flow cytometry and evaluating gene expression by WB analysis and PCR.
- The scientist will be responsible for mentoring and training post-doctoral fellows and students in the laboratory.
- The Scientist I will assist the PI in preparing figures and writing and interpreting the results of experiments.
BASIC QUALIFICATIONS
- Possession of a doctoral degree from an accredited college or university according to the Council for Higher Education Accreditation. (Additional qualifying experience may be substituted for the required education). Foreign degrees must be evaluated for U.S. equivalency)
- No work experience is required beyond the doctorate degree
- Must be able to obtain and maintain a security clearance
PREFERRED QUALIFICATIONS
- Experience or knowledge in the following:
- Hematopoiesis and hematopoietic stem cells (HSCs)
- Flow cytometry cell sorting and analysis of HSCs and their progeny
- Maintaining transgenic and mutant mouse strains
- Molecular biology techniques including cloning, RNA-seq, single cell analysis, Q-RT-PCR
- Lentiviral and retroviral vector construction and transduction
- Bone marrow transplantation
Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)
Company
A rewarding career with global impact
Whether you’re an expert in your field or just starting out, we have a career opportunity for you. We’re always looking for people to join us in fulfilling the mission of the Frederick National Laboratory: discovery, innovation, and success in the biomedical sciences.
Our team of 2,400+ scientists, technicians, administrators, and support staff work at the forefront of basic, translational, and preclinical science, with a focus on cancer, AIDS, and other infectious diseases.
We collaborate with colleagues across the National Cancer Institute, National Institutes of Allergy and Infectious Diseases, and others throughout the National Institutes of Health. We also engage with extramural investigators in academia, government and industry.
Your path to joining our team begins with the desire to work for the only national laboratory dedicated to biomedical research. Our employees share a common desire to help make a difference in cancer research and public health concerns. As you search for a career that fits your education, skills, and abilities, explore the core values that guide us and emphasize work-life balance.
Discover why joining the Frederick National Laboratory team could be the most important career step you take
- Website
- https://frederick.cancer.gov/
- Phone
- 301-846-1000
- Location
-
8560 Progress Drive
Frederick
MD
21701
US
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