Senior Scientist, Human Genetics

Employer
AbbVie
Location
Lake County, IL, US
Posted
Nov 21, 2018
Ref
1803054
Required Education
Bachelors Degree
Position Type
Full time
The Genetics Research Center (GRC) is a newly created center of excellence for genetics and genomics that supports both Discovery and Development. The GRC will play an integral role towards our goal of developing world class genetics and genomics research, focusing on finding the right targets and helping us better understand not only human disease biology but also the behavior of and response to our drugs in clinical trials. As one of the pillars of the GRC, the Department of Human Genetics is responsible for analyzing and interpreting data from large genetic sequencing databases to identify and characterize novel targets for the treatment of diseases across multiple therapeutic areas. We have an exciting opportunity for a Senior Scientist, based in North Chicago, IL reporting to the Head of Human Genetics and Clinical Genetics. The level is commensurate with experience.

Key Responsibilities Include:
  • Devise and execute studies to determine genotype-phenotype relationships from large, human sequencing databases; work with computational biologists and others to develop and provide analytical support for mining and interpreting NGS and array data across multiple projects.
  • Provide biological interpretation for genetic, genomic and epigenetic associations derived from large scale human genetic sequencing databases
  • Collaborate with Functional Genomics Group to design and execute studies to provide mechanistic understanding for genotype-phenotype relationships
  • Collaborate with scientists across different Early Discovery therapeutic areas to interpret and incorporate genetic findings into new targets or for validation of existing targets
  • Provide support for external collaborations and consortia involving human genetics


Basic:

The ideal candidate should have strong background in genetic association studies, rare disease analysis, and family based genetic studies. Candidates should have demonstrated ability to design and lead human genetics studies delivering novel genetic findings and medically relevant gene discoveries.
  • BS, MS,MD, or PhD in Human Genetics, Molecular Genetics, or closely related field, with expertise in genetic association studies, rare disease analysis, and/or family based genetic studies. 12+ (BS), 10+ (MS), or 4+(Ph.D/MD) years of relevant experience.
  • Experience working with large human genetic sequencing databases
  • Experience interpreting family-based and rare disease genetic studies
  • Experience with large-scale research projects involving next generation DNA sequencing data (e.g. whole exome and whole genome) as well as array based genotype data
  • Strong oral and written communication skills in a collaborative environment


Key Leadership Competencies:

  • Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance
  • Learns fast, grasps the 'essence' and can change the course quickly where indicated
  • Raises the bar and is never satisfied with the status quo
  • Creates a learning environment, open to suggestions and experimentation for improvement
  • Embraces the ideas of others, nurtures innovation and manages to reality


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Equal Opportunity Employer Minorities/Women/Veterans/Disabled