Bristol-Myers Squibb Company

Research Scientist

Location
Redwood City, CA, US
Posted
Nov 21, 2018
Ref
R1511764
Required Education
Masters Degree/MBA
Position Type
Full time
Research Scientist

Company
Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

Position
The department of Immuno-Oncology Discovery at Bristol Myers Squibb, Redwood City is seeking a highly motivated Research Scientist to join a group of researchers evaluating novel therapies in the field of cancer immunotherapy. The candidate will characterize immuno-modulatory antibodies, and explore mechanism of action and combinatorial therapeutic strategies.

Qualifications
  • Master degree in immunology, oncology or related field and a minimum of 4 years of experience or BS with a minimum of 7 years of experience
  • Enthusiasm about immuno-oncology research
  • Knowledge of immunology including markers, functions, and interactions of immune cell subsets, immunotherapy modalities, antibodies
  • Proficiency in the following laboratory techniques is required:
    • Immune cell isolation from whole blood (one of the following: Ficoll and MACS, RosetteSep, EasySep, etc.)
    • Functional assays with primary immune cells (myeloid, B, or T cells)
    • Multi-color flow cytometry (8 or more channels, operate BD or BC flow cytometers)
    • ELISA or ELISPOT or Luminex
    • Mammalian cell culture
    • Tissue/tumor dissociation into single-cell suspension
    • Data analysis using GraphPad/Prism and SoftmaxPro
  • Proficiency in the following laboratory techniques is strongly preferred:
    • IP/WB (immunoprecipitation)
    • Phospho-flow
  • Proficiency in the following laboratory techniques is a plus:
    • Functional assays to measure phagocytosis or NK/CD8 cytotoxicity (flow- or imaging-based)
    • Assays to evaluate bispecific antibodies or CAR-T cells
  • Excellent interpersonal skills with the ability to work both independently and collaboratively in a dynamic and innovative research environment
  • Detail-oriented, with excellent organizational, and record-keeping skills