Director, Translational Research

Beltsville, MD
Nov 19, 2018
Required Education
Position Type
Full time

Job Description

NextCure is a start-up biopharmaceutical company located in Beltsville, MD, focuses on the discovery and development of novel therapeutic biologics for the treatment of cancer.  We are seeking for a director to lead and coordinate key activities associated with translational research of NextCure’s proprietary antibody programs towards the clinic.


  • Design and execute translational research studies supporting preclinical development of NextCure’s biologics programs
  • Lead and manage pharmacology and biomarker studies for NextCure’s various programs
    • Guide a group scientists and RAs to demonstrate functionality of NextCure’s biologics in vitro/ex vivo and in vivo
    • Explore biomarker identification/validation and interface with the discovery and development teams throughout the development process 
  • Contribute to the preparation of documentation required for regulatory submissions, including INDs  
  • Assist data/slide preparation for BOD meetings
  • Present program progress at BOD meetings
  • Work closely with external research collaborators and contractors (CROs) for preclinical and clinical translational efforts
  • Closely work with discovery to facilitate the smooth and efficient transfer of required biological assays required for clinical trials 
  • Proactively participate in new target validation, including translational research assessment of emerging biology within therapeutic areas of strategic interest to NextCure
  • Manage and develop a team of professional scientists to achieve translational objectives
  • Contribute to NextCure IP filing/product portfolio development  


  • PhD in the Biological Sciences, with extensive experience in immunology, tumor cell biology and biologics product development
  • Minimum of 10 years experience (in industry is a plus)      
  • Proven track record and hands-on experience taking biological molecules through preclinical development into the clinic
  • Strong management skills with 5+ years managing a team or group of scientists, and experience leading multi-disciplinary teams
  • Solid working knowledge of research and development
  • Proven track record of leading teams in good experimental design, in-depth data analysis and interpretation based on strong scientific rationale
  • Strong publication record
  • Strong project management skills with the ability to deliver results on schedule in a fast-paced, entrepreneurial environment
  • Effective oral and written communication and interpersonal skills
  • Ability to work productively in a matrix team environment in a growing and changing environment

NextCure is an Equal Opportunity Employer and offers a competitive salary and benefits package in a scientifically engaged team work environment. Qualified candidates should click "Apply" and submit their resume.