Associate Scientist, Immuno-Oncology

South San Francisco, California
Nov 15, 2018
Required Education
Bachelors Degree
Position Type
Full time

Compugen USA, Inc., a wholly owned subsidiary of Compugen Ltd., develops therapeutic antibodies for the treatment of cancer. Working closely with colleagues in Israel, we are advancing multiple programs targeting novel immune checkpoint inhibitors for reactivation of anti-tumor immune response. We’re seeking highly skilled and motivated employees who are looking for growth opportunities in a fast paced, startup-like environment

We are seeking a highly motivated Associate Scientist to join our Immuno-Oncology Team and participate in the development and characterization of therapeutic antibodies for cancer therapy. This scientist will contribute to therapeutic programs targeting novel immune checkpoint proteins for cancer therapeutics and will play a role in the execution of the program strategy. In a matrix setting, this scientist will be responsible for in vivo studies using different mouse tumor models to elucidate the biology of novel immunology targets and to use these mouse models to identify and characterize antibodies to these targets. In this role, the scientist will have the opportunity to have a significant role in the discovery of novel drugs and their effects on target biology in the field of immuno-oncology.

• Designs, develops and executes in vivo studies with syngeneic mouse and xenograft tumor models for translation of target biology between mouse and human, and for the characterization of mouse surrogate or therapeutic antibodies
• Devises and implements multi-color flow cytometry-based strategies for immune phenotyping of mouse tumors
• Designs, develops and executes mouse cell-based functional assays for the characterization of either surrogate or therapeutic antibodies
• Assist research personnel with preparation of protocols and other documentation for submission to the IACUC and ensure timely maintenance and renewal of governing documents
• Ensure site preparedness for IACUC and other vivarium inspections
• Maintains an up-to-date understanding of the oncology and tumor immunotherapy literature and methodology, as well as the literature related to the specific antibody discovery projects
• Presents written and oral reports to the project team, Antibody R&D group, and management. Communicates research efforts to collaborators, corporate partners, and/or at scientific meetings.
• Plays a visible role in decision-making process on cross-functional antibody discovery teams; providing core expertise and input on scientific direction
• Develops and contributes to company’s intellectual property domain by way of patents and/or publications.
• Collaborates with scientific colleagues in Israel

• Bachelors, Masters, or Ph.D. in Immunology or related field

• Minimum 6 years (Bachelors), 4 years (Masters), or 0-2 years (Ph.D.) of post-graduate experience is required, preferably in the field of immunology or oncology
• Prior experience with in vivo mouse models relevant to cancer drug development and immune
functions is a must
• Extensive experience in flow cytometry-based technologies is required
• Prior core team membership experience in antibody drug development preferred
• Experience managing staff is a plus
• Track record of scientific accomplishment as evidenced by quality and quantity of publications and/or inventions
• Demonstrated ability to independently manage functional responsibilities on therapeutic project teams

• Demonstrated proficiency and knowledge in the relevant field
• Excellent written and verbal communication skills
• Ability to prioritize and manage multiple projects and activities while meeting ambitious deadlines
• Highly motivated, efficient, and ambitious; and contributes to strategic planning
• Maintains excellent working relationships with colleagues and collaborators
• Experience with a global company a plus
• Ability to travel (up to 5 %)
• Ability to work productively with colleagues across the global company