Bristol-Myers Squibb Company

Sr. Research Investigator

Location
New Brunswick, NJ, US
Posted
Nov 15, 2018
Ref
R1510708
Required Education
Doctorate/PHD/MD
Position Type
Full time
As a Sr. Research Investigator in the Drug Product Science & Technology - Materials Science and Engineering Group, the main responsibilities will be in characterization of particle and powder properties to guide robust drug substance and drug product development, and in support of tech transfer and validation for commercial manufacture. Primary activities will include characterization of materials properties such as particle size, surface area, and morphology, as well as method development, validation, and transfer. It is expected that the candidate will work in GMP and non-GMP settings with a broad range of materials, including crystalline and non-crystalline small molecule APIs, drug product intermediates and excipients, and biologics.

Expertise in characterization techniques such as surface area (BET), particle size (LLS), microscopy (SEM) is expected, as well as experience with Malvern Mastersizer 2000 and 3000 in a GMP environment. Experience in particle size method development, validation, and transfer is also expected. Understanding of additional particle analysis techniques and instruments (HIAC, MFI, Malvern Morphologi G3, Sympatec) and solid state characterization techniques (PXRD, DSC, TGA, spectroscopic techniques) is preferred.

Requirements:

Ph.D. in physical chemistry, materials or pharmaceutical science, chemical engineering, or related discipline, with 3-6 years of pharmaceutical/chemical industry or related experience or a BS/MS with 7-9 years of pharmaceutical/chemical industry or related experience. The successful candidate will have excellent problem-solving skills and a strong background in assessment of powder properties, materials characterization, and GMP environments.

The individual will effectively interface and collaborate across drug substance, drug product and analytical development teams. The individual must have a demonstrated ability to identify and solve problems. Outstanding oral and written communication skills with the ability to provide technical input and scientific leadership are required. This position requires employees to work with or come in contact with chemical agents which may pose health or safety hazards if improperly handled.