R&D Specialist, ES Cell Screening

Location
Tarrytown, New York, US
Posted
Nov 15, 2018
Ref
14545BR
Required Education
Associate Degree
Position Type
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases . Summary. We are looking for a R&D Specialist in our VelociGene group. To exploit the power of mouse genetics to unlock the function of each gene in the genome, Regeneron scientists developed VelociGene®, a proprietary group of technologies for the modification of the mouse genome . Eliminating or modifying a single gene in the mouse genome can provide insight into the role that gene plays in normal physiology and disease pathogenesis. The high-throughput of the automated VelociGene technology enables it to provide, as the name implies, the fastest path from gene discovery to assignment of function. In support of the Regeneron drug development programs, VelociGene has delivered unprecedented speed and capacity for the validation of therapeutic targets and the creation of animal models for human disease. Utilizing VelociGene in conjunction with our VelociMouse® method, Regeneron is able to vastly increase the speed and reduce the cost associated with the generation of genetically engineered mice for understanding the function of each gene . The versatile VelociGene technology enables the tackling of projects ranging from a single base mutation to multi-gene deletions and the replacement of mouse genes with their human homologs. The pinnacle of the VelociGene technological achievements was the largest mammalian genetic engineering project ever accomplished . the creation of the VelocImmune™ mouse - a mouse capable of producing human antibodies that can serve as specific and potent therapeutics . We are looking for a R&D Specialist to join the Screening Group at VelociGene. The primary responsibility will be performing experiments utilizing state-of-the-art molecular technologies for screening of mouse and rat embryonic stem cells as well as iPS cells and participation in our Technology Development efforts. Job duties/expectation Essential duties and responsibilities include but are not limited to the following . Consistently follows appropriate robotic methods for TaqMan PCR setup and demonstrates the ability to summarize and analyze data with accuracy . Contribute to identifying and troubleshooting routine screening related problems and/or optimizing processes . Routinely interprets data and recognizes anomalous results . Conduct high-throughput automated DNA isolation from mouse embryonic stem cells . Capable of multi-tasking across assignments and operates effectively in the face of ambiguity and change . Organize and compile results into a finished format for presentation . Maintain scientific curiosity and familiarity with current advances in transgenic and genome engineering technologies and literature, and apply such knowledge toward development of new or improved technologies #LI-CB1 #LI-CB1. Requirements. This position requires a minimum of a BS/MS in biology, molecular biology, or related biological sciences with 5 years of experience. In addition, we require . Experience necessary in qPCR TaqMan technology . A good understanding of mammalian genetics is essential . Experience in the area of genome engineering including CRISPR/Cas9 technology. Hands-on knowledge of molecular biology and recombinant DNA technology is a bonus . Experience and knowledge of basic bioinformatics methods, such as DNA sequence analysis and comparison, database searching, vector construction and primer design is recommended . Preferred computer skills include . word processing, spreadsheets, graphing, database management . Strong collaborative and communication skills . Ability to learn new technologies . Ability to work well in a team . This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business . To all agencies . Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid . Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.