Sr. Scientist, Stem Cell Biology

92121, San Diego
Nov 01, 2018
Required Education
Position Type
Full time

Our client, a leader in DNA solutions, is seeking a Sr. Scientist for their Stem Cell Biology group.


  • Lead a high-performance technical and support team on reproductive biology projects.  Responsible for derivation and maintenance of primary cells, adult stem cells, and pluripotent stem cells (ESC/iPSCs) for various therapeutic programs.
  • Responsible for process development of primary cells, adult stem cells, and pluripotent stem cells.
  • Execute high throughput screens to assess functionality and differentiation ability of stem cells and gene-modified stem cells.
  • Actively collaborate with other CEU teams, other intrexon divisions and external research and commercial partners as applicable to support technology transfer and collaborative projects.
  • Maintain expert knowledge of current literature.
  • Propose continual process improvements for efficiency and quality.
  • Prepare technical reports and make clear and succinct scientific presentations that can be shared and transferred to and from cross-functional teams.
  • Perform other duties as assigned.

MANAGEMENT RESPONSIBILITIES (if candidate level determines)
Supervise 1-3 employees

  • Provide leadership, drive change, and execute on the company’s mission and core values.
  • Cross-train and coach staff to maintain an efficient, lean, and knowledgeable team.
  • Coordinate and lead regular project meetings.
  • Create a weekly and daily schedule for the team; coordinate individual and teamwork assignments that foster innovation and produce results.
  • Create SMART (specific, measurable, attainable, relevant, and time-bound) metrics for the team to follow and monitor their advancement on projects under rapidly shifting priorities and timelines.
  • Ensure relevant safety protocols and instructions are readily available and strictly adhered to.


  • Ph.D. in stem Cell Biology, developmental biology, reproductive biology, Molecular Biology, or related field.
  • Minimum two years’ experience, industry experience preferred.  
  • Extensive expertise in pluripotent stem cell culture, in particular adult stem cells, ES cells, iPS cells.
  • Characterization, maintenance and differentiation of pluripotent stem cell lines.
  • Working experience on iPSC derivation. Working experience on bovine iPSC derivation is a plus but not required.
  • In depth knowledge of early developmental biology and reproductive biology.
  • Experienced in the development of ESC/iPSC differentiation protocols.
  • Working experience with cell purification methods (FACS or similar technologies) required.
  • Hands-on experience with image-based, high-throughput screening.
  • Proven track record in process improvements and technical troubleshooting.
  • Strong oral and written communication skills and an ability to communicate complex concepts in a concise, simplified manner.
  • Demonstrated attention to details and ability to effectively manage own projects and priorities.
  • Supervisory/management experience a plus.
  • Experience using high-content, image-based software analysis systems is a plus.
  • Must be a team player and comfortable in fast-paced environment.