Intern - QC Virology

Location
Rensselaer, New York, US
Posted
Oct 31, 2018
Ref
14394BR
Required Education
Doctorate/PHD/MD
Position Type
Part time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Project Description: This project is aimed around developing a next generation sequencing (RNA-Seq) approach to characterize and quantify endogenous retrovirus-like particles (RVLPs) from CHO-K1 cells. QC Virology recently developed a workflow to perform native RNA-Seq using the MinION sequencer from Oxford Nanopore Technologies. The intern will be responsible for adapting this procedure to target RVLP transcripts within the host cell and then sequence the captured sequences.

Once the method is established, the intern will be required to collect experimental RVLP RNA sequencing data for transcript characterization and establish a method to quantify the amount of full length transcripts. The internship will conclude by having established a method/assay for RVLP characterization to support requirements for cell bank characterization per ICH Q5A. The intern will be required to research relevant methods, design and carry out experiments, and present results internally with the supervision of intern buddy and lead PI.
Desired Majors and/or Skills:
- Majors: Molecular Biology, Biology, Protein Biochemistry, Genetics.
- Next-generation Sequencing (specifically RNA-Seq), Experience handling RNA templates, Lab Experience, Molecular techniques, PCR, DNA/RNA extraction and isolation, electrophoresis.

Desired Education Level:
- Rising Sr. to PhD.

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.