Research Associate II

Location
Frederick, MD, USA
Posted
Oct 25, 2018
Ref
JR106-41082
Discipline
Science/R&D, Research
Hotbed
BioCapital
Required Education
Bachelors Degree
Position Type
Full time
LHRI - The Laboratory of Human Retrovirology and Immunoinformatics (LHRI), Clinical Services Program, Applied/ Developmental Directorate, has investigated mechanism multiple drug resistance (MDR) of HIV and innate immune response against HIV or HIV related virus infection collaborating with National Institute of Allergy and Infectious Diseases (NIAID).

To support developing novel immuno or chemo therapies for MDR-HIV infected patients. LHRI has discovered that Interleukin-27 (IL-27) as a novel anti-viral cytokine and multiple novel micro RNAs as anti-viral RNAs. In addition, LHRI found a novel innate immune response/pathway against viral infection.

KEY ROLES/RESPONSIBILITIES

Assays related to this position include but are not limited to following: DNA, RNA and protein extraction, immunofluorescence, real-time PCR, Western blotting, transfection, transformation, cloning of genes of interest, construction of expression vectors, reporter assays and establishment of cell lines.

The Research Associate II will be directly supervised by a Scientist and will:
  • Independently perform multiple tasks in basic research handling infectious material under BL2* lab settings
  • Be involved in developing/standardization of new assays and evaluate the reliability of the methodology
  • Be responsible for data and quality control evaluation
  • Formally report data/results, including presentation in scientific conferences and/or publications.


BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
  • Possession of a Bachelor's degree from an accredited college or university according to the Council for Higher Education Accreditation. (Additional qualifying experience may be substituted for the required education). Foreign degrees must be evaluated for U.S. equivalency
  • In addition to the education requirements, a minimum of five (5) years of related biomedical experience
  • Ability to function independently in a research environment with minimum supervision, requiring originality and judgment; independently evaluate the suitability and quality control of research
  • Molecular biology, biochemistry, immunology, microbiology and/or cell biology
  • Experience in advanced data reporting techniques using PowerPoint and statistical analysis software
  • Experience working under sterile conditions and following safety procedures
  • Must be able to obtain and maintain a security clearance


PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:
  • Basic knowledge of HIV biology.
  • Experience purifying and culturing primary human monocytes/lymphocytes.
  • Molecular biology skills: Protein/DNA/RNA extraction, Western blotting, real-time PCR.
  • Experience in epifluorescence or confocal microscopy, from sample preparation to image acquisition and processing.


Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)