Research Associate/Senior Research Associate/Associate Scientist: Analytical and Formulation PD

Location
98052, Redmond WA
Posted
Oct 24, 2018
Required Education
Bachelors Degree
Position Type
Full time

Department: Analytical and Formulation PD

Reports To: Senior Associate Scientist 

Located in Redmond WA, Systimmune Inc. is a fast-growing bio-pharmaceutical company focused on the treatment of cancer through developing novel therapeutic multi-specific antibodies, as well as antibody-drug conjugates (ADC's). Our objective is to create biologics that work through systematic intervention on the solid tumor micro-environment, to either directly attack the tumor and/or to activate the immune system to attack the tumor.

Summary

We are seeking an energetic and highly motivated analytical research associate/senior associate/associate scientist with experience in protein formulations to join the Analytical and Formulation Development group. Standard protein/antibodies analytical skills are required for this position. Protein/antibodies formulation experience is a plus. Other than executing formulation studies, this position also provides the opportunities of leading formulation developments of various novel antibody-based molecules.

Job Responsibilities:

The major responsibilities of this position include the development of novel antibodies formulations. The successful candidate will develop and use stability indicating analytical and characterization methods, plan and execute pre-formulation studies and formulation development, analyze and interpret high quality data, and generate related reports for team meetings in a timely and efficient manner. The candidate will also need to generate SOP and related GMP documents to support successful implementation of process technology in clinical/commercial manufacturing operations. This position will also provide the opportunities of developing and conducting analytical methods to support upstream and downstream production process development.

Qualifications:

• A BS or MS in Chemistry, Biochemistry or related discipline with 2+ years of industrial analytical experience.

• Knowledgeable in protein sciences.

• Hands on experience in analytical and characterization methods including UPLC/HPLC methods (SEC, CEX, HIC), CE-SDS, cIEF, osmolality, viscosity, solubility, DLS/SLS, and other related biophysical techniques.

• Experience in liquid and frozen formulation development of antibody or non-antibody proteins is a plus.

• Experience with ADC characterization and formulation development is a plus.

• Proficient in Microsoft Word, Excel, and Power Point.

• Experience in writing Standard Operating Procedures (SOP) and relevant cGMP documents.

• Flexibility, excellent organizational skills and strong scientific problem-solving skills are required to enable successful execution of critical studies against tight deadlines.

• Excellent communication skills. Strong collaboration capability to work with other group members and departments to meet project timelines in a fast-paced team environment.