Scientist, Cellular Immunotherapy, CAR-T

Location
Cambridge, MA, United States
Posted
Oct 23, 2018
Ref
907539
Hotbed
Genetown
Required Education
Doctorate/PHD/MD
Position Type
Full time
Join bluebird bio's enthusiastic and collaborative Cellular Immunotherapy team by contributing to the overall success of our novel gene-based immunotherapy approach. This new Scientist will join our group to design, develop and evaluate novel cellular immunotherapy approaches for clinical applications.

About the job:

  • Work in a team focused on preclinical development of cellular therapeutics
  • Design and develop immunological assays to characterize genetically engineered primary T cells
  • Potential to lead a team of 1-2 research associates
  • Coordinate research projects evaluating strategies to improve efficacy of cellular therapeutics
  • Prepare all technical reports needed in support of an exploratory project moving to process development
  • Exercise independent judgment in development of new methods, techniques and evaluation criteria
  • Effectively interface with other scientific groups in bluebird bio to facilitate the success of projects


About you:

  • PhD in molecular or cellular immunology
  • 2-5+ years' experience beyond PhD as a post-doc in immunology or tumor biology
  • Applied experience in T cell therapies a plus
  • Expertise in mammalian cell culture, with specific experience isolating and propagating in vitro culture of human/mouse T lymphocytes
  • Experience with flow cytometry of primary human cells - cell sorting experience a plus
  • Experience with immunological assays to assess T cell function
  • Experience in working in animal models of adoptive immunotherapy a plus
  • Ability to work as part of a team, collaborating with members of other functional groups
  • Understanding of safe lab practices and BSL requirements
  • Excellent computer skills and experience with Microsoft Excel, Flow cytometry data analysis software, and Graphpad Prism essential
  • Superb organizational and communications, both written and oral, skills and "do-what-it-takes" attitude
  • Independently motivated, detail oriented and good problem solving ability
  • Excellent organizational skills, sufficient to multi-task in an extremely fast-paced environment with changing priorities
  • Be ready to embrace the principles of the bluebird bio culture: b colorful, b cooperative, and b yourself