Arch Oncology is an immuno-oncology company developing next generation anti-CD47 antibodies for the treatment of cancer. These anti-CD47 therapies represent a new class of checkpoint inhibitors that bridge the innate and adaptive immune systems to attack cancer. Arch Oncology has developed a functionally diverse antibody platform and is advancing a novel anti- CD47 antibody, AO-176, to the clinic that not only acts as an immune checkpoint inhibitor, but also selectively kills tumor cells (non ADCC). The team is a highly motivated group of experienced scientists and emphasizes a collaborative approach. Arch Oncology is funded by top-quality venture capital investors.
The Arch Oncology research labs are located in the Cortex Innovation Community in St. Louis, MO, near the Washington University School of Medicine and St. Louis University. Arch Oncology also has offices in the San Francisco Bay Area, CA. This position will be located in St. Louis.
Reports To: Director, Research
Job Description and Responsibilities:
- Scientist/Lab Manager with extensive experience in a academia, biotech or pharma setting, with the later two settings preferred.
- Perform as key point person for cell culture. Able to carry a large number of standard cancer cell lines in culture while maintaining consistency of those cells and their master cell banks in order to provide researchers with quality cells for subsequent experimentation.
- Perform other standard molecular, biochemical and biologic techniques associated with in vitro characterization of anti-cancer antibodies. (ex. Flow cytometry, ELISA, Western Blotting, cell-based assays etc.).
- Coordinate the organization and efficiency of the laboratory while overseeing routine lab operations to ensure efficient work flow and compliance with regulations, including safety regulations.
- Manage purchasing and maintenance of lab equipment and supplies.
- Maintain thorough and accurate scientific records.
- The expected balance between bench work and laboratory management is 60:40 respectively.
Position Requirements and Experience:
- B.S or M.S in biological sciences and preferably cancer biology, pharmacology, immunology, or related discipline.
- ~5 Years prior work experience required.
- Experience in mammalian cell culture, assays and aseptic technique; transfection and stable cell line production.
- Maintains a command of relevant scientific literature.
- Strong collaborative skills; well-organized; goal oriented; effective in a multidisciplinary team environment.
- A strong work ethic, drive, pro-activeness and ability to execute and multi-task activities with minimal supervision.
- Strong problem-solving and analytical skills.
- Ability to work independently in a fast-pace environment.
- Excellent written and verbal communication skills.
- Exemplifies honesty, ethics, and integrity.
Arch Oncology is an Equal Opportunity Employer and does not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class.