Bristol-Myers Squibb Company

Associate Research Scientist, Protein Crystallization

Location
Princeton, NJ, US
Posted
Oct 18, 2018
Ref
R1509812
Required Education
Bachelors Degree
Position Type
Full time
Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. Driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

RESPONSIBILITIES REQUIRED:
As a key member of the Molecular Structure & Design group, the successful candidate will be responsible for crystallization, purification and characterization of recombinant proteins utilizing knowledge of conventional and affinity chromatography methods, gel electrophoresis, crystallization, and general laboratory procedures. As a member of a team involved in the early stages of discovery, the position requires close collaboration with molecular biologists, protein scientists and structural biologists as well as scientists working in the various disease biology and translational areas within preclinical research. The candidate must be self motivated, possess excellent communication skills, and work both independently as well as in teams. Personal attributes of integrity and scientific creativity are required.

MAJOR SKILLS REQUIRED:
• BS/MS in Biochemistry, Structural Biology or related field plus 2-6 years of experience of industry or academia
• Carry out protein crystallization experiments, crystallization optimization, crystal harvesting for proteins and protein ligand complexes.
• Utilize crystallization automation equipment (liquid handlers, drop setters, imagers, etc.)
• Carry out protein purification / characterization as well as a thorough understanding of protein chromatography principles.
• Capable of independently designing experiments, generating data and interpreting results; demonstrated ability to work in a team environment.
• Possesses strong communication skills - be a good listener, have strong, concise, and consistent written and oral communication skills.
• The following skills, while not required, would be a plus
o Ability to independently troubleshoot purification systems and protocols.
o Experience in E. coli fermentation and protein expression.
o Experience in X-ray data collection and knowledge of X-ray structure analysis is a plus.