Manager, Vector Process Development

Location
Cambridge, MA, United States
Posted
Oct 12, 2018
Ref
967157
Hotbed
Genetown
Required Education
Bachelors Degree
Position Type
Full time
Join bluebird bio's enthusiastic and collaborative team by contributing to the overall success of our novel gene therapy and immuno-oncology approaches. The chosen candidate will have the opportunity to lead and manage an established laboratory that provides end-to-end manufacturing of non-GMP Lentiviral Vector at bench and pilot scales to enable advancement of bluebird bio's pipeline.

We seek candidates with a proven ability to successfully lead a team or workstream in a dynamic environment; working independently, proactively and collaboratively across functions to enhance product quality, quantity, process efficiency, and team efficiency. This includes managing, and/or supporting day to day planning and execution of lab activities for a team of associate scientists. The candidate will interface with multiple groups across the organization.A strong operational and technical background in bioprocessing, chemical engineering, and/or associated field will be utilized in the role, as well as experience managing and mentoring.

Primary responsibilities:

  • Develop and mentor a team
  • Oversee the planning and execution of lab activities as well as provide hands on support for execution or troubleshooting
  • Follow and promote adherence to bluebird bio's safety policies, procedures, and general safe lab practices
  • Interact with cross functional stakeholders to gather production needs, schedule productions, and provide timely communication of updates.
  • Coordinate with internal functions or external vendors for procuring raw material and consumables, equipment maintenance, analytical assay requests etc.
  • With guidance from senior management, implement a strategic vision for fulfilling future business needs (eg. increased demand, new process technologies, etc.)

About You:
  • BS or MS in a scientific discipline with 8+ years of related experience in manufacturing or process development operations role is required
  • Experience in (or understanding of) a wide range of upstream and downstream unit operations is required. Key examples: Aseptic cell manipulations, bioreactor operation, harvest clarification, AKTA operation, TFF operation, and final filtration
  • Understanding of analytical methods (qPCR, ELISA, and/or flow cytometry) for biologics, or more specifically vaccine development, is preferred
  • Demonstrated experience (2+ years) of direct supervision is preferred
  • Knowledge of GLP/cGMP/ICH/FDA practices and pharmaceutical drug development is preferred
  • Demonstrates strong leadership, mentorship, and sense of ownership
  • Highly collaborative team player who fosters open communication and facilitates mutual understanding and cooperation between all stakeholders
  • Superb organizational, analytical, and communications skills with familiarity of the MS Office suite
  • Track record of completing deliverables within specified timelines.
  • Self-directed individual who can work with limited direction in a fast-paced, goal-oriented environment.
  • Proactively proposes creative solutions to challenging timelines and competing priorities
  • A passion for addressing the critical unmet medical needs of patients
  • Willingness to embrace and demonstrate the principles of the bluebird bio culture:b colorful, b cooperative,andb yourself