Eli Lilly and Company

Biologist-Immunology Research

San Diego, CA, United States
Oct 11, 2018
Required Education
Position Type
Full time
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world

The Eli Lilly Biotechnology & Immunology research group focuses on discovering innovative biotherapeutic medicines treating autoimmune diseases and related complications. We are seeking a highly motivated and dedicated scientist with extensive knowledge and experience of cellular and molecular immunology, who also shares our passion to help patients live with higher quality of life. You will report to a Ph.D senior scientist in the group located in Lilly San Diego, CA and work in a highly team-oriented and collaborative environment. You will need to be able to work independently to design, develop and validate immunology cell-based functional assays with the goal to deliver preclinical data to support novel therapeutics for future clinical testing, and to investigate the mechanism of action of biological and small molecule therapeutics

Key Objectives/Deliverables:
  • Develop immune functional cell-based assays using extensive immunology research- related technologies (e.g. primary human and mouse lymphocytes, cytokine assays, multi-color flow cytometry)
  • Screen and analyze data for protein or small molecule drugs in cell-based assays
  • Investigate cellular signal transduction, develop cellular activity assays, cytokine/receptor signaling (western, qPCR, intracellular staining, phosphor flow cytometry, confocal/image related techniques)
  • Evaluate molecules in animal disease models to provide efficacy evidence to advance molecule for future clinical testing
  • Isolation, purification and culture of human, rat and mouse immune cells for in vitro assays.
  • Independently design and execute experiments, analyze, interpret and present experimental data
  • Adherence to good research practices, and laboratory e-notebook maintenance

Basic Qualifications
  • Bachelor's of Science or Master's of Science in biology, molecular and cellular immunology or a related biological area
  • At least 1 year of research experience in an academic institute or pharmaceutical industry
  • Qualified candidates must be legally authorized to be employed in the United States. Lilly does not anticipate providing sponsorship for employment visa status (e.g., H-1B or TN status) for this employment position

Additional Skills/Preferences
  • Extensive research experience of immunology and molecular biology. Previous experience in purification and handling of primary human and mouse lymphocytes
  • Multi-color flow cytometry
  • You should also understand and have experience with various in vivo animal autoimmune or inflammatory disease models

Additional Information
  • This position will be located at Lilly Biotechnology Center, San Diego, CA
  • Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status