Bristol-Myers Squibb Company

Research Investigator I

Princeton, NJ, US
Oct 11, 2018
Required Education
Position Type
Full time
Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. Driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Position Overview:

We are seeking an innovative scientist to join our NGS and Proteomics support team in the Translational Bioinformatics group. This group of computational scientists is responsible for advancing Bristol-Myers Squibb's industry-leading pipeline in multiple therapeutic areas (including Immuno-Oncology, Cardiovascular, Fibrosis, and Immunoscience) through the strategic application of cutting-edge bioinformatics approaches.

The scientists in this group analyze real-world health data, design experiments and analyze both pre-clinical and clinical -omics data sets, including RNA-Seq, Exome and Whole Genome Sequencing, single-cell sequencing, high-throughput proteomics, and multiplex flow cytometry in order to nominate novel drug targets, enable patient enrichment strategies, and guide drug development decisions. The group interacts with and influences all aspects of R&D at BMS, from early discovery through late-stage development. This position will focus exclusively on direct support to the CGG (Clinical Genetics and Genomics) group.

  • Assist with NGS data QC
  • Evaluate novel NGS workflows
  • Provide technology development related analysis
  • Facilitate communication between CGG and NGSP groups
  • Provide access to Seven Bridges cloud computing platform to CGG members and help implement and maintain CGG specific pipelines
  • Provide assistance to CGG with NGS and cloud computing expertise

  • Ph.D. in Bioinformatics, Computational Biology or another relevant field or M.Sc. in one of the same fields and 3+ years of experience in the field
  • Extensive experience with RNASeq and/or DNASeq workflows and pipelines
  • Extensive hands on experience with common NGS tools (samtools, picard, etc.)
  • Experience with R graphing solutions
  • Background in statistics is preferred
  • Fluency with Linux-based high-performance computing environments, R/Bioconductor, and reproducible research practices
  • Strong problem-solving and collaboration skills, and rigorous and creative thinking
  • Excellent written and oral communication skills, including an ability to explain complex ideas to computational scientists, experimentalists, and clinicians
  • The ability to work across organizations to define and solve problems that will benefit the whole. Capable of establishing strong working relationships across the organization
  • Familiarity with Seven Bridges and/or DNANexus cloud computing platforms is desirable