Scientist I/II, Cancer Immunology
REVOLUTION Medicines discovers and develops new drugs that translate frontier cancer targets through exceptional drug discovery delivering revolutionary medicines on behalf of cancer patients. Our innovative science draws inspiration from nature and evolution, which offer insights into cancer targets, disease mechanisms and therapeutic approaches. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer.
- As a key player in our biology team, you will:
- Integrate a deep knowledge of tumor biology and immunotherapy to support discovery and development of novel immuno-oncology therapies.
- Use immunology and tumor biology techniques to perform cutting-edge studies, in vitro and in vivo, to interrogate key scientific questions about established or candidate drug targets and therapeutic mechanisms.
- Independently design and execute experimental strategies, using cellular and molecular immunological techniques, to investigate target biology and therapeutic mechanisms of action in in vivo immuno-oncology models.
- Collaborate with biochemists, cell biologists and pharmacologists to generate novel insights that fuel drug development as a member of a cross-functional project team.
- Manage and analyze experimental data and present experimental results at internal meetings and scientific conferences.
- Establish collaborations with leading academic research groups in the tumor immunology field.
- Represent REVOLUTION Medicines with external organizations.
Required Experience, Skills, and Education:
- Ph.D. degree in immunology, cancer biology or a related discipline with demonstrable track record of excellence in tumor immunology and/or immunotherapy (Scientist I). Post-doctoral, or relevant industry experience, (Scientist II) will be considered but not necessary.
- Strong track record of research productivity as evidenced by high-quality, impactful publications, in the field of cancer biology and/or tumor immunology.
- Previous experience with in vivotumor growth assays is required. Knowledge of models that interrogate and modulate cells and mediators of the innate and adaptive immune system would be an advantage.
- Extensive hands on experience in ‘state of the art’ cell biology techniques including multi-parameter flow cytometric analyses, cytokine analysis, functional immunology assays, imaging and molecular biology. Knowledge of manipulation of human PBMCs and functional assays with human immune cells would be an advantage. Bioinformatic skills and familiarity with data analysis from techniques like NanoString, scRNAseq or cyTOF is a plus.
- Rigorous, quantitative and detail-oriented experimentalist with a desire to continue in a laboratory-focused role
- Excellent written and verbal communication skills.
- Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.
- Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high energy, small company environment.