Associate Scientist II, Analytical Development and Quality Control, CMC Biologics, Oncology Early De

Redwood City, CA, US
Oct 10, 2018
Required Education
Bachelors Degree
Position Type
Full time
Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica®, Venclexta™, and Empliciti™ - and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer.

AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments.

This position will be based at AbbVie Biotherapeutics (ABR), AbbVie's Center of Innovation in Oncology Research and Development, located in Redwood City, CA. ABR R&D efforts focus on two key areas:

  • Immuno-Oncology (I-O): developing therapeutics that activate the immune system to recognize and eliminate cancer cells
  • Antibody drug conjugates (ADCs); antibodies conjugated to potent toxins for directed delivery to cancerous cells while sparing healthy tissues.

We are seeking an Associate Scientist II to join the Analytical Development Group within the Oncology Early Development CMC Biologics Organization. In this role, your responsibilities will primarily include analytical testing, method development, and protein characterization via peptide map, mass spectrometry, and HPLC methodologies to support development of innovative protein-based biotherapeutics.

The successful candidate should have a BS or MS degree in analytical chemistry, biochemistry, biology or a related field with 1-3 years of post-graduation biopharmaceutical industry experience. The candidate should possess a good understanding of protein chemistry and monoclonal antibodies. The candidate must have demonstrated proficiency in peptide mapping and mass spectrometric analyses (intact protein, peptide mapping) as applied to CMC development of therapeutic proteins. Experience developing analytical methods is a plus, but not required. It is essential that the candidate have good verbal and written communication skills, be meticulous in documentation, and possess excellent troubleshooting and interpersonal skills.

Keywords: Mass Spectrometry, Peptide Map, HPLC, Liquid Chromatography, Protein Chemistry, Analytical Development

Equal Opportunity Employer Minorities/Women/Veterans/Disabled