Senior Research Associate, Biology - Immunology & Inflammation

Employer
Celgene
Location
Cambridge, MA, US
Posted
Oct 06, 2018
Ref
1803405
Required Education
Bachelors Degree
Position Type
Full time
Other Locations:US- MA- Cambridge

Description

Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing we look for talented people to grow our business, advance our science and contribute to our unique culture.

Summary/Scope

The Translational Development group is seeking a self-motivated, energetic, detail-oriented candidate with strong background in cellular immunology and molecular biology. The focus of this position will be to 1) develop and perform assays using human blood/biopsies or rodent blood/tissues that will help determining the extent of target engagement achieved with drug development candidates and 2) assist in the generation and analysis of omics data that will help identifying patient stratification strategies for specific drug targets for immunological, inflammatory and/or fibrotic diseases. The individual will participate in a broad range of programs in a dynamic, small research group and be comfortable working in a fast paced environment. Strong problem solving and time management skills are essential to complete diverse assigned tasks. Industry experience is preferred.

Responsibilities will include, but are not limited to, the following:

Design, plan, and execute blood/tissues based assays and troubleshoot existing protocols with guidance Perform high quality and well controlled immunological assays with human and animal blood or tissues including cell stimulation, cytokine analysis, and flow cytometry with minimal supervision Support scientists in execution of proof-of-concept studies. Generate and independently analyze multi-parameters data sets using appropriate analytic programs Maintain well written and accurate research electronic notebook detailing work undertaken Comply with laboratory safety procedures

Skills/Knowledge Required:

Experience in working with blood and tissues from human and animal for the study of immunological/inflammatory responses Strong hands-on experience with immune cell activation and characterization assays, multi-parameter flow cytometry, ELISA, ELISpot, RT-PCR, DNA/RNA preparation, immunoprecipitation, and western blotting. Proficiency with FlowJo, Prism, and Microsoft office applications Possess a thorough knowledge of experimental design and underlying scientific principles Excellent organizational, record keeping, oral and written communication skills Team player, detail oriented and organized

Qualifications:

Bachelor's degree in a scientific discipline with at least 4 years work experience or Master's degree with at least 2 years work experience.

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Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.