Investigative Toxicology Technician III

Employer
AbbVie
Location
North Chicago, IL, US
Posted
Oct 03, 2018
Ref
1806615
Discipline
Science/R&D, Toxicology
Required Education
Bachelors Degree
Position Type
Full time
Essential Job Function/Description
  • Participate in the conduct of exploratory toxicology animal studies according to protocols, including dosing animals and collecting samples
  • Conduct laboratory tests including pathology and microscopy techniques (tissue processing, slide preparation, immunohistochemistry, in situ hybridization) and basic molecular biology and biochemical assays (RT-PCR, Western blots, ELISA) to understand the relevance of safety findings of experimental compounds
  • Partner with molecular toxicologists and other discovery scientists to obtain materials for analysis
  • Familiarity with other investigative assays to include in vitro cell culture techniques and image analysis
  • Participate in the design and conduct of experiments to identify and characterize toxic liabilities of lead candidates and investigate mechanisms of action: design experiments, generate protocols and relevant end points, analyze data, recommend solutions for issues
  • Provide timely analysis and interpretation of data, communicate data and interpretation to project stakeholders, and help prepare reports
  • Respond quickly to information learned from ongoing experiments and provide input to project stakeholders to guide project direction and prioritization
  • Ensure proper documentation and archiving of all data generated
  • Comfortable working independently as well as part of a team with peers to achieve the assigned goals

Skills Required
  • Experience with procedures necessary for in vivo studies such as dosing and sample collection methods
  • Experience with basic analytical, molecular biology, and biochemical procedures and cell biology tools with emphasis on histologic processing of tissues and immunohistochemistry expertise
  • Entry-level technical familiarity with advanced microscopic techniques, in particular transmission electron microscopy and laser-capture microscopy
  • Good oral and written communication and interpersonal interaction skills
  • Ability to bridge between multiple disciplines
  • High comfort level working in a fast-paced team environment


Level will be based on education & years of experience

Education and Experience
  • BS in Cell Biology or Toxicology
  • 2 years' experience working with laboratory animals and histologic tissue processing; professional certification is desirable but not required

Equal Opportunity Employer Minorities/Women/Veterans/Disabled