Intern - Process Sciences

Location
Rensselaer, New York, US
Posted
Oct 02, 2018
Ref
14383BR
Required Education
Masters Degree/MBA
Position Type
Part time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Project Description: The First goal of this intern project is to create a universal small-scale column packing method to build dynamic small-scale packing procedures. The second goal is to examine the current capabilities of process analytical technologies to differentiate between poor column packs and process variability on those packed columns.

With the lack of understanding of packing parameters, resources and efficiency is wasted into packing a small-scale column. The intern will responsible for packing small-scale chromatography columns using various packing methods. Different packing parameters (i.e. slurry concentration, compression factors, packing flow rates, buffer types, different resins, and column sizes) will be analyzed to create a universal small-scale column packing method with a high level of repeatability.
The second part of the project will include performing chromatography runs on each column to model manufacturing column stresses. A control column will be packed to manufacturing specifications; this column will be processed using varying parameters such as column loading to produce atypical chromatographic results. Transition Analysis will then be used to differentiate between columns experiencing atypical features due to packing inconsistencies, and atypical features due to the varying processing parameters.
Desired Majors and/or Skills:

• Chemical Engineering major.

• Experience with chromatography/protein purification.

Desired Education Level:
- Rising Junior, Rising Senior, or Master's in Engineering Candidate.

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.