Research Associate - Oncology Bispecific ADC's

Location
Tarrytown, New York, US
Posted
Sep 28, 2018
Ref
14411BR
Required Education
Bachelors Degree
Position Type
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Summary
The Oncology group is looking for a Research Associate. The succesful candidate will play a key role in developing second generation bispecific antibody-drug conjugates, studying therapeutic antibodies against cell surface oncogenes and performing arrayed CRISPR screens.
The qualified individual will have a background in cell biology and some experience working with mice.

Responsibilities
This position requires in vitro and in vivo work
In vitro skills:
Ability to simultaneously culture multiple cancer cell lines and maintain stocks of frozen cells
Experience in various cell biology and biochemistry assays, including but not limited to western blotting and immunoprecipitation, cell surface binding assays, internalization assays, cell killing assays, FACS, ELISA, etc.
Knowledge of CRISPR technology; experience with RNA manipulation, molecular cloning, transfections and PCR.
High content and confocal microscopy experience is a plus

In vivo skills:
Perform in vivo tumor studies
Protein/RNA extraction from mouse tissue and tumors for downstream assays

Managerial:
Maintain a clean, organized lab space.
Organize refrigerated space and make reagent inventory periodically.
Execute experiment, analyze results, troubleshoot whe necessary.
Propose ideas for technical or biological advancement.
Ability to work independently and in collaboration.
Maintain Electronic Leb Notebook (ELN) records

Core Competencies:
Highly organized and able to keep updated records of large high-content datasets.
Good oral and written communication skills
Strong knowledge in design and execution of cell-based experiments
Achieves goals in a timely manner in a fast-paced, dynamic multidisciplinary environment
Knowledge of cancer biology
Requirements
Bachelor's degree and 3 years experience in industry

Cell culture, molecular cloning, transfections, western blot, microscopy, cell killing assays, high content microscopy, in vivo tumor studies, processing of animal tissues

This position will require the individual to pass a physical before beginning employment.

Level will be commensurate with experience.

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.