Research Associate I-II, Formulation Development

Location
Tarrytown, New York, US
Posted
Sep 28, 2018
Ref
14413BR
Required Education
Associate Degree
Position Type
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Summary
Research Associates (RA) in the Formulation Development Group work in a state-of-the-art laboratory developing formulations for protein-based drug products and provide support to research, pre-clinical, clinical and manufacturing teams to move drugs from candidate selection and preclinical development to clinical development and commercialization. RAs will be responsible for evaluating novel delivery technologies, including controlled release formulations.

Responsibilities

• Participate in synthesis, development, and assessment of existing or novel delivery systems for use with protein-based drugs for preclinical and Phase 1 clinical studies, and developing formulations or Phase 2/3 clinical studies and commercialization.

• Support development and stability testing of complex formulations with proteins and biomaterials

• Assist in the design and execution of studies to evaluate physicochemical properties of proteins, protein stability, and elucidate protein degradation mechanisms

• Work in cross-functional teams to support toxicology and PK/PD studies

• Implement analytical methods for proteins and biomaterials to support formulation development

• Maintain analytical equipment and support other lab organization tasks

• Process and analyze data and assist in writing, reviewing and editing technical reports

Requirements

• BS or MS degree in Biomedical or Chemical Engineering, Pharmaceutical Sciences, Chemistry, Biochemistry or related field with at least 1-3 years of academic research or industry experience in a laboratory setting

• Ability to work independently or in a team setting; strong problem solving skills; quickly adapts to change to support accelerated timelines; efficient time management

Preferred:

• Experience with controlled release formulations and applications, such as micro/nanoparticles, hydrogels, polymers, liposomes, devices, etc.; preferably with proteins or peptides.

• Basic understanding of common protein degradation pathways. Prior research experiences in the areas of protein structure, stability, and protein aggregation are a plus.

• Hands on experience with analytical, chemical or physical characterization of proteins and/or biomaterials

• Experience with analytical methods and instrumentation, such as U/HPLC-based chromatographic techniques (especially SEC, IEX, RP, GPC-MALS), electrophoretic methods (cIEF, MCE-SDS, SDS-PAGE), particle characterization methods (MFI, SEM), Raman, rheometer

• Experience with biophysical methods, such as laser diffraction, DLS, DSC, FTIR, UV-Vis, CD and fluorescence spectroscopy

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

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