Bristol-Myers Squibb Company

Translational Research Investigator

Cambridge, MA, US
Sep 27, 2018
Required Education
Position Type
Full time
Cambridge, MA

Bristol-Myers Squibb R&D is a science-driven, passionate organization determined to discover, develop and deliver medicines that have the potential to transform the lives of patients and establish new standards of care in areas of high unmet need. Patients' needs and scientific discovery are our driving force. The new Bristol-Myers Squibb research site in Cambridge's Kendall Square will position our scientific team in the heart of a vibrant ecosystem of world-class science, innovation and business opportunities. Our scientists will focus on novel targets and pathways for tumors that are refractory to current Immuno-Oncology therapies. These are significant challenges that will require innovative solutions from the biopharma, biotech and academic communities.

Role / Responsibilities

We are seeking an experienced scientist to join our Translational Research group in our new state-of-the-art facility. The qualified candidate is a highly motivated, interactive, and creative individual that possesses the ability to work across a highly matrixed environment to advance the translational research efforts. The candidate will be expected to implement the preclinical translational program, involving the development of humanized systems to validate novel targets and testing combination strategies to elucidate underlying mechanisms of resistance. The role requires effective collaboration with colleagues in the oncology, immunology and immuno-oncology groups, as well as liaising with the wider translational medicine, discovery and clinical teams. To be at the forefront of elucidating and overcoming resistance to IO therapies, should encourage scientists who are passionate problem solvers and thrive on a challenge that is clinically-vital, to consider this opportunity.

  • PhD in Cancer or Molecular Biology, or equivalent advanced biology degree
  • Experienced scientist with 3-5+ years' of post-graduate research experience, with a minimum of 2 years post-doctoral studies in a clinical or translational setting
  • Candidate will have in-depth knowledge / understanding of various mechanisms of therapeutic response and resistance utilizing in vitro , in vivo and novel ex vivo patient-derived models
  • Participated in clinical studies to better characterize the molecular underpinnings of therapeutic resistance in patient cohorts and correlation with clinical outcome
  • A track record of independent critical thinking and scientific achievement demonstrated by first authorship in recent high impact publications
  • Exposure to cancer immunotherapy including immune-checkpoint blockade with knowledge of current therapeutic landscape is highly desirable
  • Recent experience in supervising scientists in an academic or industry setting is desirable
  • Experience in balanced experimental design, data visualization and basic statistical analysis are desirable
  • Excellent interpersonal skills and ability to communicate, both written and oral effectively and efficiently within the BMS organization and with external partners/collaborators
  • Thrives in fast-paced, dynamic work environment, bringing a pro-active mentality to the role

We follow the science and we'll continue to invest in translational medicine research, deepen our understanding of disease biology and uncover insights about predictive biomarkers with the ultimate goal of making precision medicine a reality for more patients.