Principal Research Scientist, GI Immunology

Worcester, MA, US
Sep 24, 2018
Required Education
Bachelors Degree
Position Type
Full time
The Immunology Discovery organization is responsible for identification of new therapeutic approaches for the treatment of autoimmune diseases. We have an exciting opportunity for a Principal Scientist based in Worcester, MA reporting to the Director of Pharmacology.

We are seeking a dynamic and innovative leader to guide the development and implementation of mechanism of action, PK/PD, biomarker and pharmacology assessments across a range of preclinical approaches. Expert knowledge in immunology, especially IBD/GI Disease, and the design and conduct of both in vitro and in vivo models of autoimmunity and inflammation are essential.

The successful candidate will lead a group of scientists in the Immunology Pharmacology Department. Some of the responsibilities include:

  • Provide strong scientific, technical, and organizational leadership to drive IBD/GI disease drug discovery and related immunology disease areas.
  • Provide detailed knowledge of the pathophysiologic mechanisms of IBD/GI disease and apply this knowledge to implement new concepts and methodologies for the development of drug candidates.
  • Drive excellent performance of group by effectively managing both direct and indirect reports including recruiting, managing, mentoring and developing scientific staff
  • Contribute to defining research team goals by collaborating with scientists within and outside functional area

  • BS, MS, PhD or DVM in biological sciences with 16-18+ (BS), 14-16+(MS, or 8-10+ (PhD) years of postdoc/industry experience
  • Established track record of delivering multiple candidates to development
  • Recognized leader in pharmacology with in-depth knowledge of in vitro assay systems and disease models and ability to establish PK/PD correlates
  • Experience in managing direct reports and development of scientific staff with positive team building and teamwork skills
  • Evidence of strategic thinking and portfolio management a plus
  • Ability to manage and maintain scientific business relationships and contract research agreements
  • Strong written and oral communication skills
  • Outstanding track record of publications

Equal Opportunity Employer Minorities/Women/Veterans/Disabled