Senior Scientist, Attribute Science, Product Sciences

Employer
Celgene
Location
Warren, NJ, US
Posted
Sep 18, 2018
Ref
1803157
Required Education
Doctorate/PHD/MD
Position Type
Full time
Other Locations:US- NJ- Warren

Description

Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

Senior Scientist, Attribute Science, Product Sciences

Cell Therapy Development & Operations

The Principal Scientist in Attribute Science group within Product Science Team, Cell Therapy Development & Operations (CTDO) at Celgene carries the responsibilities for supporting cellular therapy product pipeline development via characterization of products and defining critical quality attributes (CQAs). Specifically, the incumbent is responsible for developing analytical methods for characterization of cell therapy products, both from internal Celgene pipelines and from third-party collaborations, from candidate nomination through lifecycle management, and looking for correlations with clinical outcomes in collaboration with Translational Development (TD). This individual will be a key member of the Attribute/Product Science group and is anticipated to make significant contributions to advance biological and mechanistic understanding of cellular therapeutic products.

Responsibilities include, but are not limited to:

  • Lead a team of junior scientists with responsibility for product characterization, including assay development, high-throughput screening, and data analysis.
  • Manage and mentor junior scientists and provide input into personnel decisions including performance appraisals, promotions, hiring, and other personnel related activities.
  • Contribute to the scientific, technical and operational efforts within Attribute/Product Science with regards to product characterization, CQA definition, new assay conceptualization, selection, and method development.
  • Share responsibility for the group's scientific and technical standards, critical review of documentation and reports, and setting analytical strategy to support product development.
  • Interpret data clearly and concisely in documents and present results in an organized manner.
  • Identify and apply novel technology and expertise to enhance analytical capability for product and process characterization.
  • Work closely with Molecular Profiling and New Biology groups to design and execute in vitro studies to advance cell therapy product knowledge and define product attribute candidates.
  • Interface and collaborate closely with process and analytical development to support CMC development and advance cellular therapy pipelines.
  • Communicate with project team and colleagues effectively and work well with others to meet experimental and organizational goals.
  • Pursue externalization of scientific results through publication and presentation to the broader scientific community.
  • As required, conduct due diligence and otherwise support business development initiatives to add assets to the Celgene cellular immunotherapy portfolio.


Skills/Knowledge Required:

  • Ph.D. in relevant scientific discipline required.
  • Strong cellular immunology background with the emphasis on T cell biology.
  • Expertise and experience in adoptive T cell therapy is preferred.
  • Minimum 5 years of relevant experience in the biotechnology or pharmaceutical industry with exposure to cell therapy or biologics development.
  • Demonstrated ability for critical thinking, problem solving and innovation.
  • Effective communication, collaboration, and negotiation.
  • Proven ability to work effectively with cross-functional stakeholders in a complex/changing global environment.


Education Requirements:
  • Ph.D. in relevant scientific field with at least 5 years of relevant experience in the biotechnology or pharmaceutical industry


#LI-POST

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.