Scientist / Senior Research Associate
Tacere Therapeutics Inc., a wholly owned subsidiary of Benitec Biopharma, is currently seeking a highly motivated and dynamic candidate to fill a Scientist or Senior Research Associate position in the R&D group. Tacere is a rapidly growing biotech company located in the Britannia Point Eden Business Park in Hayward, CA with convenient access in the bay area as it is located just off of the San Mateo Bridge. Tacere is focused on the development of novel human therapeutics based upon RNA interference (RNAi). More information about the company can be found at "http://www.benitec.com"
Requirements will be for a PhD. A BS or MS level candidate will be considered if they have commensurate experience for the job activities.
Primary responsibilities will include:
Producing research grade lots of AAV (Using triple transfection, baculovirus- or HSV based processes)
In vitro and in vivo characterization of AAV vectors using biochemical and molecular approaches
Position will also support GLP/GMP manufacturing and managing related projects at third party external sites
Design, construction, and evaluation of new AAV vectors and capsids
Required skills and qualifications:
Must possess considerable hands-on experience in protein purification using AKTA (FPLC) system. The experience with AAV is a plus
Fundamental understanding of commonly used molecular methods and strong laboratory skills with a diverse range of product characterization methods relevant to biologics and gene therapy based products, including
*cell based assays
*protein or vector analysis by gel electrophoresis (protein and DNA), ELISA, Western blotting, quantitative PCR, Nucleic acid extraction and quantification
Proven ability to work independently in a hands-on laboratory setting
Self-motivated to learn and develop new techniques, multi-task, maintain accurate records, develop procedures, and comply with company’s policies
Comfortable with responsibilities in an entrepreneurial, fast–paced, start-up company environment
Excellent oral and written communication skills including expertise with computer software commonly used in biotech research and development
Strong team player who works closely and effectively with colleagues
A dynamic and highly collaborative working environment. Comprehensive benefit package available, including health, dental, vision, and 401K. Job title and compensation will be based on candidate experience.
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