Technology Development Research Associate
Caribou Biosciences, Inc. is a leading company in CRISPR genome engineering located in Berkeley, CA. Caribou's tools and technologies provide transformative capabilities to therapeutic development, agricultural biotechnology, industrial biotechnology, and basic and applied biological research. The six-year-old company has developed a best-in-class CRISPR genome engineering technology platform and has a leading intellectual property position.
We are seeking an enthusiastic and motivated Research Associate (RA) to join our Technology Development group. The individual in this role will interact closely with Scientists and other RAs to drive discovery and optimization of genome-editing based therapeutics in pre-clinical development. Primary responsibilities will include design and generation of materials for mammalian cell transfections and analysis of next generation sequencing (NGS) data from genome editing experiments. Overall, the ideal candidate will be familiar with published genome editing work, as well as have a strong background in molecular biology and next-generation sequencing (NGS).
Responsibilities will include:
- PCR (design and implementation)
- RNA transcription/reverse transcription and other relevant enzymatic assays
- Formulation of ribonucleoprotein (RNP) complexes and other relevant materials for mammalian cell transfection
- In collaboration with core facilities, prepare and analyze Illumina sequencing libraries
- Compile data and present results
- Stay current on relevant primary literature
Candidate must possess:
- B.Sc. or equivalent in Biochemistry, Cell Biology, Bioengineering, or Molecular Biology
- Minimum of 2-3 years’ experience working in either Academic Laboratories or the Biotech Industry
- Understanding of genome editing technologies
- Hands-on experience with RNA transcription, enzymatic assays, and NGS
- Highly familiar with genome editing technologies and underlying concepts
- Familiarity with experimental design and strong organizational skills
- Excellent written and verbal communication skills
- Hands-on experience with mammalian cell transfections
- Understanding of DNA repair mechanism and pathways
- Experience designing low and medium throughput screens
- Familiarity running FACS analysis for cell surface phenotyping
Caribou Biosciences, Inc. is a dynamic start-up company, and the successful candidate must have the ability and desire to work in a fast-paced environment. For more information, please visit www.cariboubio.com. Caribou is on Twitter. Sign up to follow our Twitter feed @CaribouBio.
Caribou offers a comprehensive compensation package, as well as generous paid time off in addition to Company-observed holidays. The Company provides medical, dental, and vision insurance, along with a 401(k)-retirement savings plan which includes matching employer contributions. Caribou promotes a culture in which employees are respected and rewarded for hard work, innovation, personal initiative and teamwork.
Caribou is an equal opportunity employer and does not unlawfully discriminate on the basis of race, color, religion, citizenship, political activity or affiliation, marital status, age, national origin, ancestry, physical or mental disability, medical condition (as defined under California law), veteran status, sexual orientation, gender identity, gender expression, sex or gender (which includes pregnancy, childbirth, breastfeeding, or related medical conditions), taking or requesting statutorily protected leave, or any other basis protected by law. In addition, Caribou prohibits the harassment of any individual on any of the bases listed above or any other characteristics protected under federal, state or local laws.