Director - Head of Neuroscience

Location
94089, Sunnyvale
Salary
Competitive Salary and Benefits
Posted
Sep 02, 2018
Ref
Head of Neuroscience
Required Education
Doctorate/PHD/MD
Position Type
Full time

Director, Head of Neuroscience

NeuCyte, Inc. – Sunnyvale, CA

Who we are:

NeuCyte is an early stage biopharmaceutical company that focuses on developing treatments for those suffering from neurological and neurodegenerative disorders. We develop translatable cell-based assays for modelling neuro related disorders using patient-derived and genetically-engineered neural cell types to discover novel therapeutics. Based on our SynFire technology, our proprietary human neural in vitro platforms assess complex electrophysiological and morphological readouts suited for target identification and validation, as well as drug efficacy testing.

What we’re looking for:
NeuCyte is seeking a highly motivated Director of Neuroscience to join our neuro drug discovery team. The successful applicant must have a neurobiology and neurophysiology background with strong drug discovery experience. Applicants must be able to keep up with the fast pace of a small biopharmaceutical and work on multiple projects at a time.

What you’ll do:

  • Work with a multidisciplinary team to optimize our in vitro human iPSC derived neural disease models.
  • Lead the Neuroscience team to design, execute and build target discovery assays and conduct in-vitro pharmacology studies using new biochemical, cell-based and phenotypic assays, such as high-content imaging and MEA analysis to support NeuCyte’s internal drug discovery programs and advancement of lead molecules.
  • Participate in business development efforts resulting in the acquisition of innovative assets and/or enabling technologies that enhance NeuCyte’s discovery research pipeline.
  • Participate in the development, design and execution of non-clinical studies to support advancement of our programs.
  • Propose new programs/diseases/areas of science that could be considered for future portfolio expansion.
  • Coordinate with collaborators and CROs, as needed, to manage in vitro experiments and set clear goals and expectations for the broader team.
  • Establish and manage relationships with academic collaborators and/or CROs, including development of research plans and data analysis.
  • Review scientific literature to remain up to date of developments in relevant fields.
  • Recruit, develop and retain world class scientists, building a strong research team as evidenced by pipeline productivity and external scientific reputation.

Required:

  • PhD/MD related to neuroscience, pharmacology, molecular biology, or genetics with 10+ years of drug discovery industry and supervisory experience.
  • Track record of innovation in the discovery of therapeutics for neurodegenerative and synaptic driven disorders with a strong emphasis on leveraging human genetics.
  • Strong scientific contributions in target discovery and validation using genomic and small molecule screening as evidenced by quality and quantity of publications/ presentations/ inventions and clinical candidates.
  • Experience managing day to day activities in research and development, with direct responsibility for meeting program timelines and budgets.
  • Highly motivated cross-functional team player who is flexible with ability to work in a fast-paced environment.
  • Mentor and develop individual talent capable of taking on future leadership roles.
  • Clear written and verbal communication skills with excellent record keeping.

Compensation:

  • Competitive salary and benefits.