Scientist 3, Strain Engineering

Location
Emeryville, CA
Salary
120K - 140K base salary, benefits and bonus
Posted
Aug 30, 2018
Ref
2624
Required Education
Doctorate/PHD/MD
Position Type
Full time

Scientist 3, Strain Engineering

Amyris is seeking a Biological Scientist to engineer, evolve, and optimize microbes for industrial fermentations to deliver sustainable solutions for a growing world. The Scientist will join a team of researchers utilizing the world’s most advanced high-throughput, automated strain engineering and testing platform. The successful candidate will formulate hypotheses, design experiments, interpret data, and design, build, and test microbial strains and enzymes to improve strain performance in industrial fermentation conditions.

Responsibilities

  • Work with a team to develop a new manufacturing strain & process for innovative, sustainable bio-manufacturing
  • Design strains, experiments, and screens to understand and remove barriers to high strain performance
  • Work with researchers from the automated strain engineering, high-throughput screening, analytical chemistry, fermentation, and bioinformatics groups to build and test engineered strains
  • Analyze scientific literature and in-house historical data to identify and examine hypotheses to improve strain performance; collaborate with bioinformatics/AI group to deepen learning from large datasets
  • Analyze data from rich phenotype + genotype datasets, and apply knowledge of cellular metabolism and physiology, to design additional DNA designs (i.e., genotypes) for the next round of strain engineering
  • Manage and coordinate complex experimental schedules within a broader team
  • Mentor, train, and possibly manage more junior scientists
  • Maintain safe practices and work environment

Qualifications

We require candidates with formal technical training (Ph.D. or equivalent experience) in metabolic engineering, microbiology, molecular biology, biochemistry, chemistry, chemical engineering, or a related field. The ideal candidate will have >5 years post-Ph.D. relevant experience, preferably in an industrial setting. We prefer candidates with a history of successfully engineering metabolism or signaling, and iteratively improving strain performance. Previous experience in the field of microbial genome engineering and/or synthetic biology is a plus. The successful candidate will have expertise in some or all of the following areas:

  • Cellular physiology and metabolism in microbes
  • Cellular processes involved in small molecule production, including redox balance, energetics, product transport, growth rate, fermentation conditions, overflow metabolism, etc.
  • Enzymology and protein engineering
  • Molecular biology techniques, including PCR, restriction digest analysis, design and execution of cloning experiments, DNA assembly methods, plasmid construction, DNA sequence analysis, nuclease-triggered DNA recombination, microbial transformation, and genomic DNA analyses (in bacteria and/or yeast)
  • Concepts in statistics and tools to analyze data (e.g., Excel, Minitab, R, Spotfire, JMP)
  • Experience working productively as part of a cross-disciplinary, collaborative team
  • Demonstrated high productivity and track record of research success

Amyris, a leader in industrial synthetic biology, uses its innovative bioscience solutions to achieve renewable products by converting plant sugars into hydrocarbon molecules. Amyris’ molecules are used in wide range of specialty & performance chemicals, flavors & fragrances and in applications ranging from cosmetics to biofuels. Learn more at www.amyris.com.

As a VEVRAA Federal Contractor, Amyris is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, disability status, protected veteran status, or any other characteristic protected by law. Amyris complies with applicable state and local laws governing nondiscrimination in employment.

If you are a recruiter or placement agency, please do not submit resumes to any person or email address at Amyris, Inc. prior to having a signed agreement. Amyris is not liable for and will not pay placement fees for candidates submitted by any agency other than its approved recruitment partners. Furthermore, any resumes sent to us without an agreement in place will be considered your company’s gift to Amyris and may be forwarded to our recruiters for their attention.

For a full list of our current openings, please visit our website <http://www.amyris.com/careers>.