Principal/Senior Scientist Position - Neuroscience Drug Discovery Team

94089, Sunnyvale
Competitive Salary and Benefits
Aug 29, 2018
Principal/Senior Scientist
Required Education
Position Type
Full time

Principal / Senior Scientist - Neuroscience Drug Discovery Team 
NeuCyte, Inc. – Sunnyvale, CA

Who we are:

NeuCyte is an early stage biopharmaceutical company that focuses on developing treatments for those suffering from neurological and neurodegenerative disorders. We develop translatable cell-based assays for modelling neuro related disorders using patient-derived and genetically-engineered neural cell types to discover novel therapeutics. Based on our SynFire technology, our proprietary human neural in vitro platforms assess complex electrophysiological and morphological readouts suited for target identification and validation, as well as drug efficacy testing.

What we’re looking for:
NeuCyte is seeking a highly motivated Principal/Senior Scientist to join our neuro drug discovery team. The successful applicant must have a strong neurobiology and neurophysiology background with previous drug discovery experience. Applicants must be able to keep up with the fast pace of a small biopharmaceutical and work on multiple projects at a time.

What you’ll do:

  • Work with a multidisciplinary team to optimize our in vitro human iPSC derived neural disease models.
  • They will be responsible for the development, optimization and execution of new biochemical, cell-based and phenotypic assays, such as high-content imaging, MEA analysis, to support NeuCyte’s internal drug discovery programs and advancement of lead molecules.
  • Collaborate with our target team to identify and validate new targets aligned with NeuCyte’s drug development strategy.
  • Participate in the development, design and execution of non-clinical studies to support advancement of our programs.
  • Establish and manage relationships with academic collaborators and/or CROs, including development of research plans and data analysis.
  • Review scientific literature to remain up to date of developments in relevant fields.


  • PhD with 6-8 years of closely related technical experience, preferably in a pharmaceutical or biotech lab environment.
  • Must be organized, detail-oriented, and work well in small teams.
  • Prepare protocols and SOP’s for multiple assays.
  • Must be able to assist in trouble shooting activities and process optimization under the guidance of more experienced personnel.
  • Clear written and verbal communication skills with excellent record keeping.
  • A self-motivator with the ability to handle multiple projects at once


  • Human stem cell research experience in a pharmaceutical environment
  • CNS pharmacology experience preferably in an industrial environment


  • Competitive salary and benefits