Senior Scientist, Cellular Process Development

Cambridge, MA, United States
Aug 25, 2018
Required Education
Masters Degree/MBA
Position Type
Full time
Join bluebird bio's enthusiastic and collaborative team by contributing to the overall success of our novel gene therapy approach. The Process and Analytical Development organization at bluebird bio encompasses lentiviral vector, gene editing, and cellular drug product processing for oncology and severe genetic diseases. The cellular process development team is responsible for developing cellular drug product processes and introducing new technologies for stem cell and T-cell therapies.

The focus of this position is to leverage cell culture process development expertise (e.g. proteomics, transcriptomics and metabolomics tools) to advance process understanding for our autologous cell-based processes and drive development, scale-up and technology transfer activities for robust process improvements. The Senior Scientist will lead this innovation by outsourcing and managing external projects as well as collaborating internally with subject matter experts.

About the role:
  • Lead the development of innovative technologies and apply biologics development and continuous/automated manufacturing concepts, tools, and practices to autologous cell-based gene therapy processes
  • Collaborate closely with the Lentiviral Vector Process Development group to leverage and advance shared technologies
  • Develop experimental plans, interpret scientific results, provide statistical analysis where appropriate, summarize and present scientific data and report progress on behalf of the team

About you:
  • MS/Ph.D. in Chemical Engineering, Biochemical Engineering, Cell Biology, Biochemistry or related fields with a minimum of 5 years (Ph.D.) or 10 years (MS) of relevant industry experience
  • Experience in mammalian cell culture process development and good understanding of bioprocess engineering concepts
  • Strong background in metabolomics, genomics, transcriptomics, RAMAN, and/or FACs
  • Ability to independently design, execute and interpret laboratory experiments to answer scientific questions and to execute novel and advanced scientific techniques
  • Demonstrated scientific aptitude through authorship of peer-reviewed publications
  • Ability to manage priorities, and make decisions in a fast-paced environment to make sure deliverables are achieved in a timely fashion.
  • Strong writing, editing and presentation skills required
  • Experience in statistical analysis or modeling is preferred
  • Ability to work effectively in a collaborative team environment where results are achieved through influence, cooperation, and the incorporation of multiple points of view
  • Independently motivated, detail oriented and good problem solving ability
  • Excellent organizational skills, with an ability to embrace change and multi-task in an extremely fast-paced environment
  • Excellent communications skills and ability to influence across multiple functions.
  • Be ready to embrace the principles of the bluebird bio culture: b colorful, b cooperative, and b yourself