Associate Director, Clinical Informatics

Location
Tarrytown, New York, US
Posted
Aug 23, 2018
Ref
14000BR
Required Education
Doctorate/PHD/MD
Position Type
Full time
Position Summary

The Regeneron Genetics Center (RGC) is a wholly-owned subsidiary of the Company, whose goals are to apply large scale human genetics to identify new drug targets and to guide the development of therapeutics programs and precision medicine. Building upon Regeneron's strengths in mouse genetics and genetics-driven drug discovery and development, the RGC specializes in ultra-high-throughput exome sequencing, large scale informatics and data analysis encompassing genomics and electronic health records, and translating genetic discoveries into new biology and drug discovery opportunities. The RGC leverages multiple approaches including large population based studies, Mendelian genetics and family based studies, founder population genetics, and large-scale disease focused projects and has developed a network of over 50 collaborations with research organizations around the world. Including some of the largest sequencing studies in the world, such as the DiscovEHR study in collaboration with Geisinger Health System, and an initiative to sequence 500,000 participants with the UK Biobank, the RGC has built one of the largest human genetics databases, including sequence data from over several hundred thousand participants and rapidly growing. Our interests encompass a breadth of different areas across all therapeutic areas and the RGC is highly integrated into all facets of research and development at Regeneron. Program goals include target discovery, indication discovery, and patient-disease stratification. Objectives include advancing basic science around the world through public sharing of discoveries, providing clinically-valuable insights to physicians and providers of collaborating health-care systems, improving patient outcomes, and identifying novel targets for drug development.

Summary
The position will be responsible for providing strategic leadership to the RGC's clinical informatics group. Working with the Head of Clinical Informatics, the physician informaticist will manage and develop relationships with EHR data providers such as healthcare systems and academic research networks and their informatics groups. Responsibilities will also include providing clinical input to the team of data analysts developing and executing queries for diverse stakeholders. The position will also involve working with a team of database administrators, biostatisticians, clinical scientists, and programmers to structure and mine clinical and phenotypic data sets and support genomic studies and association analyses. The position will require coordination and collaboration with other scientists within the department, research and clinical scientists at Regeneron, and external collaborators. The position will report to the Head of Clinical Informatics.

Responsibilities
-Close collaboration with internal Regeneron teams to define and refine clinical research questions and patient cohorts
- Close collaboration and coordination with external health system collaborators and informatics teams mining EMR and phenotypic data sets. Work with these collaborators to structure data and develop algorithms, rules engines, and querying tools to access and curate the phenotypic datasets.
- Provide input to a group of analysts working within a team of programmers, database administrators, statisticians, and clinical scientists, as well as external collaborators and facilitate EMR data extraction, transformation and processing from multiple health system partners.
- Represent the RGC at national meetings or in other similar settings

Requirements
This position requires an MD/DO and either board certification in clinical informatics or the completion of an NLM-sponsored fellowship. Additional requirements include:
- Familiarity with data mining, clinical databases, hospital health informatics databases including Epic or other EHR data structures, ideally through work at an academic medical center
- Familiarity with clinical data standards such as ICD, SNOMED, LOINC, and OMOP, and database architecture and administration
- Experience with HIPAA and experience with IRB protocols around use of use of EHR data.
- Experience working with investigators and ideally experience as a principal investigator with a track record of academic publication and/or federal grant support
- Involvement in relevant programs such as PCORnet, eMERGE, HMO Research Network, or other such projects is preferred.
- Demonstrates understanding of relational database concepts and query tools.
- Demonstrates strong analytical skills
- Demonstrates the ability to multitask and manage simultaneous projects to meet deadlines with a strong attention to detail.
- Demonstrates ability to interpret and communicate analytical information in a clear, concise manner.

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.