In vivo Scientist, Peripheral Indications

Location
San Carlos, CA
Posted
Aug 10, 2018
Required Education
Doctorate/PHD/MD
Position Type
Full time

This position requires leading the design, establishment, validation and implementation of in vivo functional assays via the use of surgical, behavioral and histological techniques to understand biological processes, bioactive efficacy and mechanism of action of agents in diseases of aging. Focus on both peripheral and CNS biology relevant to a range of age-related disorders will be explored.The studies performed will involve cutting edge science and require innovative concepts and techniques. This position requires exceptional judgment, communication, organization and leadership, and will interact with a team of scientists and manage research associates to drive multiple projects in parallel.This position requires leading the design, establishment, validation and implementation of in vivo functional assays via the use of surgical, behavioral and histological techniques to understand biological processes, bioactive efficacy and mechanism of action of agents in diseases of aging. Focus on both peripheral and CNS biology relevant to a range of age-related disorders will be explored.The studies performed will involve cutting edge science and require innovative concepts and techniques. This position requires exceptional judgment, communication, organization and leadership, and will interact with a team of scientists and manage research associates to drive multiple projects in parallel.

Responsibilities:  

  • Establish and validate new animal models probing processes of aging in peripheral organs 
  • Perform surgeries and relevant procedures on rodent models for therapeutic administration
  • Independent assessment of behavior and mechanisms of action of therapeutics via multiple techniques
  • Actively perform and manage laboratory based scientific research
  • Actively incorporate translational concepts for effective therapeutic development
  • Interact with scientific and management teams to define scientific path and strategies
  • Lead, supervise, manage and mentor a team of research associates to execute on goals
  • Manage external vendor contracts and studies
  • Identify and incorporate appropriate assays and technologies for enhancing therapeutic translation
  • Other responsibilities as assigned

Requirements: 

  • PhD or equivalent degree with significant laboratory experience 
  • Direct role in establishment, validation and performance assessment of behavioral and surgical assays required
  • Automated behavioral analysis and industrial environment experience
  • Experience with peripheral model development, testing, and biomarker identification required.
  • Technical knowledge for in vivo phenotyping as well as immunohistology and molecular endpoint analysis greatly preferred
  • In vivo neuroscience expertise with cognition endpoints highly beneficial
  • Expertise in inflammation/neuroinflammation desired
  • Strong communication skills
  • Inquisitive and passionate to perform groundbreaking science
  • Track record of effective leadership and project success
  • Independence in technical and conceptual experimental design and implementation
  • Excellent interpersonal, verbal and written communication skills
  • Attention to detail and strong organizational skills
  • Solid background in biostatistics
  • Strong knowledge of Microsoft Office Suite and Outlook