Pharmacyclics, LLC

Senior Manager, Operational Excellence

Pharmacyclics is committed to the development and commercialization of novel therapies intended to improve the quality and duration of life and to resolve serious unmet medical needs for cancer patients. Pharmacyclics is a wholly-owned subsidiary of AbbVie (NYSE:ABBV), a global, research-based biopharmaceutical company. Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products and a pipeline containing multiple promising new molecules that are being studied in more than 200 clinical trials for over 20 different types of cancer.

More than 1,200 Pharmacyclics and AbbVie research scientists, clinicians, marketing, operations and corporate professionals work in the San Francisco Bay Area. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. Together, we are striving to outsmart cancer.

To learn more about us, please visit us at

Senior Manager Operational Excellence

General Position Summary/Purpose:

The is an expert in business transformation and continuous improvement who is a key driver in all facets of Operational Excellence activities within Pharmacyclics Finance and Infrastructure. He/she drives business transformation and harmonization by managing Operational Excellence while building and promoting the capabilities of Operational Excellence's multiple organizational levels, and ensuring process standards are consistently applied. The role will utilize LEAN tools to develop and implement initiatives that drive gains in efficiency, improve processes/systems and overall quality, as well as teach and facilitate implementation of standard processes, methods, and tools to deliver results in organizational scalability. The Operational Excellence/Business Transformation team lead critical strategic transformation and integration.

Key Accountabilities/Core Job Responsibilities:

  • Co-leads and oversees PCYC Finance & Accounting integration projects and/or program(s).
  • Maintains the functional work programs for PCYC, monitors progress, issues, risks, activity completion and milestone achievement.
  • Liaises with the Global Process and Sub-Process Leaders, Local Process Leaders, IT, Business, Legal, Communications, HR and PCYC F&I leadership on issues and risks that need escalation
  • Manages milestones across work streams that impact the F&A Operational Excellence, transition and integration projects while co-leading deployment
  • Responsible for knowledge transfers, training, key service level definitions, critical deliverables, cut-over readiness, etc after project/system/process deployment.
  • Facilitates change management and integration project communications within the PCYC
  • Co-responsible for design, development and implementation of Operational Excellence projects including Continuous Improvement, Project Management, Communication, Change Management, and Training
  • Leads medium/large scale, enterprise-wide business transformation projects
  • Identifies, assesses, and solves complex business problems for area of responsibility, where analysis of situations or data requires an in-depth evaluation of variable factors
  • Typical OPEx engagements (not exhaustive) include operations strategy, implementation of operating models, organization design & governance, business/function transformation, scalability
  • Manages deployment of initiatives, tools, frameworks, and methodologies in the PTP, RTR, OTC, T&E workstream including process governance and LKU communities
  • Uses OPEx principles, tools, methods, and techniques, in direct support of achieving PTP, RTR, OTC business goals, improving performance, and increasing efficiency and productivity via process standardization
  • Serves as a liaison between the various cross-functional groups and F&I management to co-develop and implement the various projects and process improvements initiatives
  • Provides technical and business guidance on improvement projects to provide a continuous pipeline of improvement activities to meet the companies' annual goals and objectives
  • Uses project management and continuous improvement tools to develop mechanisms for monitoring overall program progress and to coordinate and drive the operational aspects of the various projects through implementation
  • Facilitates and coach problem solving meetings
  • Provides process and technical support in all phases of process improvement project implementation
  • Coordinates PTP, T&E, RTR, OTC communication, change management and training with internal and external stakeholders
  • Develops key relationships with functional leaders, key stakeholders, local key users and Subject Matter Experts to promote the deployment of improvement initiatives and adoption to change
  • Implements and publish PTP, RTR, OTC quantitative and qualitative key performance analyses metrics and dashboards
  • Works with leadership across the F&I organization to identify and prioritize initiatives and develop plans to implement
  • Manages directly and/or indirectly team members


  • BA/BS in Finance or Accounting, M.Sc. in Business as advantage
  • 5-8 years plus of industry or consulting experience in internal controls, project management and / or process optimization
  • Demonstrated hands-on experience in large scale ERP SAP and Global Target Operating Model implementation and post-implementation project(s)
  • Proven ability to coordinate and implement process end-to-end and continuous improvement
  • Demonstrated ability to set priorities, establish clear expectations and execute identified projects
  • Experience in the areas of process optimization, change management, process management and standardization
  • Strong influencing and relationship skills
  • Excellent root case problem solving and process mapping skill
  • Strong computer, proficient in Microsoft Office specially Excel, PowerPoint, and Visio
  • Ability to liaise with, speak and present effectively to personnel at all levels of the organization
  • Proven ability to work with cross-functional teams
  • Hands-on experience of training and coaching others to support process standardization
  • Solution driven personality, dedicated to finding pragmatic solutions to complex problems
  • Strong communication and relationship management skills, able to influence without direct authority
  • High level of social competence, ability to work in different cultures and diverse environments
  • Previous experience in the areas of Finance Operational Excellence, Finance Audit, FP&A, PTP or RTR process management/optimization
  • Proven experience in large scale PMO and/or risk management projects are required