Bristol-Myers Squibb Company

Research Investigator I

Hopewell, NJ, US
Aug 02, 2018
Required Education
Position Type
Full time
Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. Driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

We are seeking an innovative scientist to join our NGS and Proteomics support team in the Translational Bioinformatics group. This group of computational scientists is responsible for advancing Bristol-Myers Squibb's industry-leading pipeline in multiple therapeutic areas (including Immuno-Oncology, Cardiovascular, Fibrosis, and Immunoscience) through the strategic application of cutting-edge bioinformatics approaches. The scientists in this group analyze real-world health data, design experiments and analyze both pre-clinical and clinical -omics data sets, including RNA-Seq, Exome and Whole Genome Sequencing, single-cell sequencing, high-throughput proteomics, and multiplex flow cytometry in order to nominate novel drug targets, enable patient enrichment strategies, and guide drug development decisions. The group interacts with and influences all aspects of R&D at BMS, from early discovery through late-stage development.

  • Establish best practices for various DNASeq QC workflows
  • Build new DNASeq pipelines and explore new Algorithms for DNASeq analysis
  • Work on integration of data from downstream DNASeq pipelines
  • Bioinformatically support exploration of novel DNASeq assays and library preparation

  • Ph.D. in Bioinformatics, Computational Biology or another relevant field or M.Sc. in one of the same fields and 3+ years of experience in the field
  • Good working knowledge of RNASeq and DNASeq workflows
  • Extensive hands on experience with common NGS tools (samtools, picard, etc.)
  • Experience with ggplot2 and other R graphing solutions
  • Some statistics background is required
  • Fluency with Linux-based high-performance computing environments, R/Bioconductor, and reproducible research practices
  • Strong problem-solving and collaboration skills, and rigorous and creative thinking
  • Excellent written and oral communication skills, including an ability to explain complex ideas to computational scientists, experimentalists, and clinicians
  • The ability to work across organizations to define and solve problems that will benefit the whole.
  • Capable of establishing strong working relationships