Scientist, NCI Patient Derived Models Repository Distribution Quality Control Manager (NCI)
The Applied and Developmental Research Directorate (ADRD) provides clinical and biological monitoring, regulatory support, biospecimen processing and storage, assay development, and project management support to the National Cancer Institute (NCI) and National Institute of Allergy and Infectious Disease(NIAID) clinical programs, including the Division of Cancer Treatment and Diagnosis (DCTD). The NCI Patient Derived Models Repository (PDMR) provides scientific and logistical support for all aspects of patient-derived model development including tissue and clinical data acquisition, model development, model quality control and quality assurance, and model distribution.
The Scientist II, NCI Patient Derived Models Repository Distribution Quality Control Manager, will:
- Provide scientific oversight for data accuracy and quality control of all in vivo, in vitro, and organoid models being developed for internal and public distribution by NCI’s Patient Derived Models Repository (PDMR)
- Assist the PDMR Operations Manager in pathology and nextgen sequencing data review and QC for upcoming distributable models and help focus efforts of a multi-laboratory program for high-priority models and data review
- Perform scientific QC review of data in Certificates of Analysis for distributable in vitro and organoid cultures
- Oversee and track progress for internal projects utilizing patient-derived models
- Create and update standard operating procedures (sops) to keep up with a fast-paced and evolving workflow
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
- Possession of a Doctoral degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a field related to biomedical research.
- In addition to educational requirements, have at least two (2) years of experience in an in vitro or in vivo laboratory; post-doctoral training or experience is required for this position.
- Must be able to obtain and maintain a security clearance
- Strong organizational and communication skills (written and oral) and ability to author documents including manuscripts for publications, SOPs, clinical protocols, etc.,
- Proficient with Microsoft Office (Excel, Word, and PowerPoint)
Candidates with these desired skills will be given preferential consideration:
- Hands-on experience developing or validating patient derived xenograft or in vitro culture models
- Experience with SharePoint and SQL or Oracle databases
- Experience with R, SigmaPlot, GraphPad Prism
- Ability to work effectively in a team‐oriented environment
- Ability to identify and solve complex problems
- Strong multitasking skills
- Ability to collaborate with a diverse group of scientific staff responsible for data review and quality assessment.
- Outstanding English language communication skills are required. Ability to communicate with program lead researchers in a demanding scientific environment through preparation of formal reports and presentations.
- A record of publication in refereed scientific literature.