Program Leader,Sickle Cell Disease, Vice President

Cambridge, MA, United States
Jul 26, 2018
Science/R&D, Pathology
Required Education
Bachelors Degree
Position Type
Full time
Join bluebird bio's enthusiastic and collaborative team! We are leading the gene therapy revolution with integrated product platforms encompassing gene therapy, cancer immunotherapy and gene editing - providing us with the potential to treat, and hopefully cure, a broad range of serious diseases.


The PL will serve as bluebird's cross-functional leader for product development efforts for Sickle Cell Disease (LentiGlobin for SCD, as well as, other SCD programs). In this capacity, the PL will be responsible for working cross-functionally with all bluebird's Functions and partner closely with the Brand Leader and the Program Manager assigned to the team, with the overarching goal of bringing, with a strong sense of urgency, transformative treatment to patients with sickle cell disease. The PL will also work closely with the LentiGlobin Transfusion-Dependent Thalassemia (TDT) leadership to ensure alignment on strategies and plans for the LentiGlobin product. The PL will report to the COO and Head of the Severe Genetic Disease Franchise.


The SCD PL will drive the LentiGlobin SCD program through registration filings and initial commercial launches. The PL will also provide leadership to other SCD efforts, such as next generation products and evaluation of potential external opportunities. Specifically, the PL's key responsibilities include:
  • Lead shaping of the integrated strategic and operational plan for development and successful commercialization of LentiGlobin for SCD globally, in close partnership with the SCD Brand Leader. In particular, ensure identification and pressure testing of options and their risks/benefits. Ensure clarity and support by all key stakeholders on the path forward
  • Provide oversight and guide decisions on next generation SCD programs in the context of an integrated strategic plan for SCD
  • Drive key strategic program decisions and actively solicit input from team members and key stakeholders. Take ownership and accountability for engaging the right stakeholders in the decision-making process and ultimately for making decisions
  • Identify and ensure resolution of key strategic issues
  • Drive implementation of strategy and plan
  • Ensure feasibility of operational plans and resources for successful implementation
  • Work with the teams and key stakeholders to ensure clarity of responsibilities within the team/s, especially on key deliverables
  • Ensure appropriate prioritization, adequate resource allocation ($ and people), timeline planning and quality checkpoints are met to optimize SCD product/s (timelines and deliverables)
  • Champion the SCD program/s in the context of the priority in the overall bluebird portfolio.
  • Provide leadership to the Program Team (and sub-teams and working groups) within a matrix of functional leaders and representatives
  • Set the standard for collaboration and operational excellence within the program team. Build strong relationships with team members to drive trust, respect, and excellent results
  • Partner with the Program Manager to create a team environment where people are highly engaged and comfortably voice their ideas & perspectives.
  • Consistently display and drive behaviors consistent with bluebird's leadership model including:
    • Innovation driver
    • Builder and scaler
    • Strategic thinker and DOer
    • Collaborative and inspiring leader
    • Ensure transparent communications
    • Ensure timely and transparent communication on progress, risks and decisions within the teams and with key stakeholders
    • Ensure consistency in company external communications regarding SCD - US/EU/ROW
    • Represent the SCD team in internal and external events as appropriate

Education, Background and Experience
  • 15+ years of business leadership experience witha strong record of accomplishments in the biopharmaceutical industry
  • Deep understanding of drug development
  • Experience with the rare disease/orphan drugs and innovative approaches to product development and commercialization
  • Demonstrated ability to lead and influence teams and stakeholders and achieve results including leading cross-functional drug development/commercialization teams
  • Ex-US and Regional-Global experience a plus
  • Experience managing alliances (academic and industry) is a plus
  • Advanced scientific degree and background is a strong plus
  • Commercial experience and product launch experience a plus
  • Proactive and "hands on" with collaborative orientation, self -motivated and able to smoothly establish strong working relationships
  • Outstanding communication skills with both internal and external audiences and excellent interpersonal andrelationship building skills
  • Ready to embrace bluebird's values: b cooperative, b colorful, and b yourself