Scientist/Sr. Scientist, Protein Engineering

Mountain View, CA
Jul 27, 2018
Science/R&D, Research
Required Education
Position Type
Full time

Job Description

Amunix Operating Inc. is seeking a highly-driven and innovative individual to join our Research and Discovery group. The candidate will be responsible for the design and optimization of multi-specific protein therapeutics with use in oncology. He/She must be highly motivated and collaborative to thrive in a fast-paced, dynamic work environment. 

Positions Duties and Responsibilities

• Design and optimize molecules through a combination of rational design and empirical screening

• Engineer proteins (with a focus on antibody fragments) to improve folding, stability, optimize binding, and/or increase production yield

• Perform small-scale medium throughput protein expression (E. coli) and purification

• Work closely with other team members to evaluate and characterize these proteins in a variety of in vitro and in vivo models

• Function as a project leader to coordinate efforts, define timelines and deliverables


• Ph.D. in Biological Science (Molecular Biology, Biochemistry, Protein Chemistry) or a related field with at least 2 years of post-graduate experience in either an academic or industrial setting 

• Strong scientific background in protein engineering, with a focus on antibody/fragment discovery and screening (preferably yeast or phage display)

• Ability to think creatively to identify and solve scientific problems

• Extensive knowledge of the scientific literature

• The ability to manage multiple projects in parallel, to communicate clearly and effectively and build open and collaborative relationships is essential

• Experience with medium throughput protein expression and characterization (Octet or similar) is strongly preferred

• Ability to effectively work independently and effectively participate in multi-disciplinary teams

• Strong interpersonal skills and excellent oral and written communication skills

• Physical ability to lift up to 40 lbs and work at the lab bench for extended periods of time

About Amunix

We are a biopharmaceutical company developing highly innovative biotherapeutics with best-in-class therapeutic index. Amunix products are based on our ProTIA (Protease Triggered Immune Activator) and XTEN protein polymer platforms. In addition to our internal pipeline we maintain active collaborations with many top tier pharmaceutical and biotechnology companies (Roche, Celgene, Genentech, Bioverativ/Sanofi). As employee you will be able to:

• Work in a highly collaborative and motivated working environment

• Receive a comprehensive benefits package, including Health, Dental, Vision, Life Insurance, Short-term/Long Term Disability, matching 401(k) plans, and free daily lunches

• Receive compensation based on candidate experience