Senior Research Associate
Role and Responsibilities
- Generate, characterize, and optimize monoclonal antibodies to select lead candidates for development
- Apply cutting edge in vitro and in vivo immunology and oncology methodologies to evaluate activity and mechanism(s) of antibody therapeutics
- Design and conduct cell-based assays using cell lines and primary cells isolated from humans and animals
- Perform flow-cytometry based assays and analysis
- Present data at project team meetings and seminars to drive recommendations for drug discovery and/or development decisions
- Perform research and/or development in collaboration with others for projects
- Develop and perform cell-based assays to profile small molecule and antibody candidates
- Develop and perform exploratory and proof-of-concept studies using cells and small animals
- Analyze and interpret data, documents and present results
- Support the senior scientist in literature search and preparation for presentations/publications
- Manage the inventories of reagents, cells and animals for the team and assists in the general maintenance of the laboratory
- Investigate, create, and develop new methods and technologies for project advancement
- Maintain an up-to-date understanding of relevant technical literature and methodology
- May participate in scientific conferences and contribute to scientific journals
- Exercises independent judgment in selecting methods, techniques and evaluation criteria for obtaining results
- Acts independently to determine methods and procedures on new or special assignments
Qualifications and Education Requirements
- Bachelor’s degree in immunology, biology, or related field required
- 8+ years of related experience required
- Must have broad expertise in the area of antibody therapeutics, immune-oncology, cancer biology, and drug discovery/development
- Experience with antibody engineering and production methods
- Familiarity with syngeneic and xenogeneic tumor models in rodents is preferred but not required
- Experience in immuno-oncology methods, including in vitro immune functional assays.
- Demonstrated ability to work independently and manage functional responsibilities on project teams
- Work independently in an interdisciplinary, fast-paced, often changing environment.
- Demonstrated ability to collaborate, prioritize, and thoughtfully utilize resources to ensure timely and successful completion of projects
- Excellent teamwork and collaboration skills
- Proficient with FlowJo, Prism, Microsoft Office
- Able to build effective working relationships internally and externally to achieve goals.
- Flexibility and willingness to solve problems that fall outside of immediate area of expertise
- Clear and concise verbal and written communication skills and strong organizational skills, with an exceptional attention to detail.
San Francisco Bay Area candidates only!