Sr. Scientist/Scientist, Immuno-oncology

Compugen LTD
South San Francisco, California
Jul 20, 2018
Required Education
Position Type
Full time

Compugen USA, Inc., a wholly owned subsidiary of Compugen Ltd., develops therapeutic antibodies for the treatment of cancer.  Working closely with colleagues in Israel, we are advancing multiple programs targeting novel immune checkpoint inhibitors and immune modulators for reactivation of anti-tumor immune responses.  We’re seeking highly skilled and motivated employees who are looking for growth opportunities in a fast paced, startup-like environment.

Reports to the Associate Director, Immuno-oncology, working to discover and develop novel therapeutic antibodies for cancer treatment.  This scientist will lead therapeutic programs targeting novel immune modulators for cancer therapeutics, and will play a role in defining strategy of the programs.  In a matrix setting, this scientist will also be responsible for establishing in vitro assays to elucidate the biology of novel immunotherapy targets and to use these assays to identify and characterize lead antibodies to these targets.  Drug development experience, working in immuno-oncology and translational medicine, is a must.  The position will be asked to supervise research associates and provide scientific mentorship and career growth opportunities for their direct report(s). In this role, the scientist will have the opportunity to have a significant role in the discovery of novel drugs and their effects on target biology in the field of immuno-oncology.


  • Drug development experience in immuno-oncology and translational medicine is a must
  • Leads and advances therapeutic program by defining strategy and guiding team members across functions/sites and from corporate partners
  • Designs, develops and executes cell-based assays for the identification and characterization of therapeutic antibodies
  • Advances capabilities of the Antibody R&D group through development of novel screening strategies or implementation of new technologies
  • Provides expertise on flow cytometry based technologies to support Ab screening and functional analysis of immune cells
  • Devises and implements biomarker strategies for preclinical and clinical development programs
  • Maintains an up-to-date understanding of the oncology and tumor immunotherapy literature and methodology, as well as the literature related to the specific antibody discovery projects
  • Presents written and oral reports to the project team, Antibody R&D group, and management Communicates research efforts to collaborators, corporate partners, and/or at scientific meetings
  • Plays a visible role in decision-making process on cross-functional antibody discovery teams; providing core expertise and input on scientific direction
  • Supervise research associates and provide scientific and career mentorship
  • Develops and contributes to company’s intellectual property domain by way of patents and/or publications
  • Collaborates with scientific colleagues in Israel


  • Ph.D. in Immunology, Pharmacology, Cell Biology, or related life science


  • Minimum of 3 years (Scientist) or 6 years (Sr. Scientist) of post-graduate industry experience is required, preferably in the field of immunology or oncology
  • Prior experience in drug development within immuno-oncology and translational medicine is a must
  • Prior experience with cell-based assays relevant to cancer drug development and immune functions is a must
  • Extensive experience in flow cytometry based technologies is required
  • In vivo experience with in vivo models relating to tumor immunology is preferred
  • Prior project leadership experience in antibody drug development preferred
  • Track record of scientific accomplishment as evidenced by quality and quantity of publications and/or inventions
  • Demonstrated ability to independently manage functional responsibilities on therapeutic project teams


  • Demonstrated proficiency and knowledge in the relevant field
  • Excellent written and verbal communication skills
  • Ability to prioritize and manage multiple projects and activities while meeting ambitious deadlines
  • Highly motivated, efficient, and ambitious; contributes to strategic planning
  • Maintains excellent working relationships with colleagues and collaborators
  • Experience with a global company is a plus
  • Ability to travel (up to 5 %)
  • Ability to work productively with colleagues across the global company