Director, Cell-Based Assay

South San Francisco, CA
Jul 18, 2018
Required Education
Position Type
Full time

Programmable DNA, the software of Life, is finally here! Twist Bioscience is developing a disruptive Synthetic DNA technology that will change the world, enabling widespread health and sustainability. Synthetic biologists will use our products to engineer how organisms produce cures to diseases, make everyday chemicals by using the atmosphere as the carbon source, enable plants to make their own fertilizers, and to create in-vivo diagnostics that alert us when we are sick, and many more applications.

We are seeking an outstanding,  innovative, and creative Director to join our antibody discovery effort.  This director will play multiple roles within the Pharma group and will work within a team responsible for antibody discovery utilizing a number of in vitro display technologies, e.g. phage display, ribosome display, and yeast display.

What You’ll Be Doing

  • Create a best in class cell-based assay team focused on GPCRs and offer exceptional scientific and technical leadership to peers and team members
  • Oversee a team focused on generating target over-expressing GPCR cell lines and establishing and conducting GPCR functional assays for antibody discovery
  • Design and execute antibody/protein drug discovery innovative strategies
  • Manage workflow of drug discovery group to ensure quality, priorities, and timelines
  • Contribute strategically to technology and product direction
  • Work closely across disciplines and across multiple projects to support technology integration
  • Offer scientific and technical leadership within your team and cross-functionally
    Manage external collaborators and serve as a key scientific liaison with external organizations
  • Work closely to incorporate new technologies into Twist Bioscience and support technology integration across teams
  • Ensure operations are designed and sourced appropriately to enable us to achieve our ambitious goal

What You’ll Bring to the Team

  • Expertise in understanding and assessing GPCR function through cell-based assays
  • Experience in generating over-expressing cell lines using lentivirus and/or other technologies
  • Strong background in cell culture, flow cytometry, and FACS sorting
  • Your educational background includes a PhD in immunology, cell biology, biochemistry, or related discipline
  • Ability  to think  outside the  box is key
  • Minimum of 5 years of relevant industry experience
  • Experience leading a team of greater than 3 people
  • You take pride in building state-of-the-art technology capabilities and staying on top of the latest developments in the field
  • You thrive in a dynamic, quickly changing environment where we were work individually and on teams
  • You have a point of view, value your independent thinking, and are low ego

Preferred Qualifications

  • Ph.D.  with outstanding  GPCR-focused publication  record
  • Strong  desire to  work in a dynamic  start-up environment is  essential
  • Ability  to multitask  and thrive in  a fast-paced and  challenging environment  
  • Strong  organization  skills and proficiency  in computer skills including  various databases
  • Excellent  oral/written  communication and  interpersonal skills  a must
  • Your research has been published in high-impact academic journals
  • You demonstrate a track record of being strong interpersonally and with experience leading a group and overseeing multi-disciplinary projects

About Twist Bioscience

At Twist Bioscience, our expertise is accelerating science and innovation by leveraging the power of scale. We have developed a proprietary semiconductor-based synthetic DNA manufacturing process featuring a high throughput silicon platform capable of producing synthetic biology tools, including genes, oligonucleotide pools and variant libraries. Our platform overcomes the current inefficiencies of synthetic DNA production, and enables cost-effective, rapid, high-quality and high throughput synthetic gene production, which in turn, expedites the design, build, test cycle to enable personalized medicines, pharmaceuticals, sustainable chemical production, improved agriculture production, diagnostics, biodetection and data storage. For more information, please visit Twist Bioscience is on Twitter. Sign up to follow our Twitter feed @TwistBioscience at

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.