Chemist, Medicinal/Organic

Ambrx, Inc.
La Jolla, CA or San Diego, CA
Jul 18, 2018
Science/R&D, Chemistry
Required Education
Position Type
Full time

Ambrx is a biopharmaceutical company enabling a new field of protein medicinal chemistry, using a fundamentally new technology that directs incorporation of amino acids beyond nature’s conserved set into biosynthetic proteins to produce high value biologics products.  

We are seeking a highly creative and motivated Medicinal/Organic Chemist with biological experience to be a key member of a dynamic fast-paced research organization.


The successful candidate will support our peptide/small molecule synthesis, analysis of structure-activity relationships and protein conjugation by delivering high quality data and method development. He/she will also be involved in cross-functional communications with biotechnology discovery and pharmacology group to characterize the in vitro/in vivo activity of toxin/peptide conjugates. Contribute to patent applications and IND filings as required.


Education Qualification:

Ph.D. in Medicinal/Organic chemistry, biochemistry or related field required with at least 2-6 years’ industry or post doc. experience. 

Range of technical expertise:

  • Proven track record in drug discovery showing creative ideas and good vision;
  • Extensive experience in modern organic synthesis, SAR and hands-on skills in using analytical and purification equipment such as HPLC, LC-MS, NMR;
  • Experience in state-of-art peptide synthesis, ADC or chemical biology is a plus.
  • Excellent communication, organization and collaborative skills are essential. 

To be considered as an applicant, please submit your resume/CV referencing the specific position of interest.  Applicants whose qualifications and experience most closely match the requirements of the position will be reviewed.  Candidates will only be contacted for evaluative discussions.

Ambrx offers competitive compensation & benefits.