Bristol-Myers Squibb Company

Associate Research Scientist I, In Vivo

Location
Princeton, NJ, US
Posted
Jul 14, 2018
Ref
R1507115
Required Education
Bachelors Degree
Position Type
Full time
The successful candidate will join the Integrated Oncology Discovery Research team at Bristol-Myers Squibb in Lawrenceville, NJ and aide in the advancement of early stage therapeutics in tumor immuno-biology.

The qualified candidate is a highly motivated, interactive, and creative individual that possesses the ability to work across a highly matrixed environment to advance preclinical drug development programs from target identification/validation through IND enabling activities. The candidate will be expected to effectively collaborate with colleagues in the oncology, immunology, immuno-oncology, protein engineering/antibody development, pharmaceutical optimization, and chemistry groups. The successful candidate will demonstrate clear and professional verbal and written communication, capable of presenting scientific results to multidisciplinary teams and key stakeholders.

Responsibilities include
  • Contribute to the execution of rodent in-vivo pharmacology experiments, including but not limited to model development, tumor implantation, including orthotropic implantation, surgery, animal identification and randomization, dosing via IV, IP, SC, I-TUMOR and PO routes, tumor measurements by caliper, weighing, health monitoring, tissue sampling by fine needle biopsy and core needle biopsy, peritoneal lavage, blood draws by retro-orbital, tail vessel micro-sampling, cardiac puncture and tissue/tumor collection at necropsy including fixation, freezing and tissue disaggregation to support ex vivo analyses
  • Contribute to the development of new pharmacology models under supervision of senior scientists
  • Accurately maintain proper scientific documentation associated with pharmacology studies in an electronic lab notebook.
  • Ability to effectively communicate and present summaries of research results to team members or to a multidisciplinary team of researchers.
  • Work as a member of a diverse and motivated team of researchers spanning across multiple divisions of the in vivo discovery unit.
  • Rotating weekend, holiday and off-hour on-site responsibilities to support BID/QD dosing will be expected of this position.


Qualifications:
  • A B.S. with at least two years relevant industry experience and a clearly demonstrated skill set in oncology, immuno-oncology, or immunology is required. Competency in injection techniques through PO, IP, IV, and SC administration is highly desired.
  • Excellent organizational skills and a detail-oriented approach to the execution of experiments and record keeping is a requirement. Strong interpersonal skills with the ability to interact effectively with peers and management, both internally and externally is required.
  • Hands-on experience with in vivo mouse models is required; experience with cancer cell implantation is preferred. Ability to effectively engage with members of a cross-functional team.