Scientist, Cell-Based Assay

San Francisco, CA
Jul 03, 2018
Required Education
Position Type
Full time

Programmable DNA, the software of Life, is finally here! Twist Bioscience is developing a disruptive Synthetic DNA technology that will change the world, enabling widespread health and sustainability. Synthetic biologists will use our products to engineer how organisms produce cures to diseases, make everyday chemicals by using the atmosphere as the carbon source, enable plants to make their own fertilizers, and to create in-vivo diagnostics that alert us when we are sick, and many more applications.

We are seeking an outstanding,  innovative, and creative Scientist to join our antibody discovery effort. This scientist will play multiple roles within the Pharma group and will work within a team responsible for antibody discovery utilizing a number of in vitro display technologies, e.g. phage display, ribosome display, and yeast display.

What You’ll Be Doing

  • Generating target over-expressing cell lines for antibody discovery work
  • Establishing and conducting functional assays on antibodies
  • Plan, perform, analyze, and document laboratory experiments in support of antibody discovery
  • Evaluate and support the implementation of new technologies
  • Maintain laboratory instruments
  • Work collaboratively under aggressive timelines

What You’ll Bring to the Team

  • Expertise in understanding and assessing GPCR function through cell based assays
  • Strong background in cell culture, flow cytometry and FACS sorting
  • Successful candidates will be independent and creative researchers, capable of experimental design, execution, and troubleshooting
  • Your educational background includes a PhD in immunology, cell biology, biochemistry, or related discipline
  • Motivation  to learn new  scientific techniques  and to work in a team  environment is necessary
  • Ability  to think  outside the  box is key
  • Minimum of 3 years of relevant post-doctoral and/or industry experience

Preferred Qualifications

  • Ph.D.  with outstanding  GPCR-focused publication  record; Postdoctoral experience  preferred (Industry experience can  substitute)
  • Experience in screening anti-GPCR antibodies in functional assays preferred  
  • Experience expressing antibodies in HEK293/CHO and purifying them using traditional methods preferred
  • Strong  desire to  work in a dynamic  start-up environment is  essential
  • Ability  to multitask  and thrive in  a fast-paced and  challenging environment  
  • Strong  organization  skills and proficiency  in computer skills including  various databases
  • Excellent  oral/written  communication and  interpersonal skills  a must
  • Extensive experience with ELISA assays
  • Ability to multitask
  • Excellent problem-solving capabilities
  • Extraordinary attention to detail and planning
  • Outstanding oral and written communication skills
  • Proficiency with Microsoft Word, Excel, and PowerPoint

About Twist Bioscience

At Twist Bioscience, our expertise is accelerating science and innovation by leveraging the power of scale. We have developed a proprietary semiconductor-based synthetic DNA manufacturing process featuring a high throughput silicon platform capable of producing synthetic biology tools, including genes, oligonucleotide pools and variant libraries. Our platform overcomes the current inefficiencies of synthetic DNA production, and enables cost-effective, rapid, high-quality and high throughput synthetic gene production, which in turn, expedites the design, build, test cycle to enable personalized medicines, pharmaceuticals, sustainable chemical production, improved agriculture production, diagnostics, biodetection and data storage. For more information, please visit Twist Bioscience is on Twitter. Sign up to follow our Twitter feed @TwistBioscience at

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.